A nuclear chocolate box: the periodic table of nuclear medicine

被引:109
作者
Blower, Philip J. [1 ]
机构
[1] Kings Coll London, St Thomas Hosp, Div Imaging Sci & Biomed Engn, London SE1 7EH, England
基金
英国惠康基金; 英国工程与自然科学研究理事会;
关键词
POSITRON-EMISSION-TOMOGRAPHY; IN-VIVO EVALUATION; IMAGING AGENT; COPPER-64; RADIOPHARMACEUTICALS; BIFUNCTIONAL CHELATORS; RADIONUCLIDE GENERATOR; FILLED MICELLES; CELL-LINE; COMPLEXES; THERAPY;
D O I
10.1039/c4dt02846e
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Radioisotopes of elements from all parts of the periodic table find both clinical and research applications in radionuclide molecular imaging and therapy (nuclear medicine). This article provides an overview of these applications in relation to both the radiological properties of the radionuclides and the chemical properties of the elements, indicating past successes, current applications and future opportunities and challenges for inorganic chemistry.
引用
收藏
页码:4819 / 4844
页数:26
相关论文
共 186 条
[1]   Preclinical evaluation of 227Th-labeled and 177Lu-labeled trastuzumab in mice with HER-2-positive ovarian cancer xenografts [J].
Abbas, Nasir ;
Bruland, Oyvind Sverre ;
Brevik, Ellen Mengshoel ;
Dahle, Jostein .
NUCLEAR MEDICINE COMMUNICATIONS, 2012, 33 (08) :838-847
[2]   Tetraamine-Derived Bifunctional Chelators for Technetium-99m Labelling: Synthesis, Bioconjugation and Evaluation as Targeted SPECT Imaging Probes for GRP-Receptor-Positive Tumours [J].
Abiraj, Keelara ;
Mansi, Rosalba ;
Tamma, Maria-Luisa ;
Forrer, Flavio ;
Cescato, Renzo ;
Reubi, Jean Claude ;
Akyel, Kayhan G. ;
Maecke, Helmut R. .
CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (07) :2115-2124
[3]   Radiohalogens for imaging and therapy [J].
Adam, MJ ;
Wilbur, DS .
CHEMICAL SOCIETY REVIEWS, 2005, 34 (02) :153-163
[4]   Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer [J].
Afshar-Oromieh, Ali ;
Zechmann, Christian M. ;
Malcher, Anna ;
Eder, Matthias ;
Eisenhut, Michael ;
Linhart, Heinz G. ;
Holland-Letz, Tim ;
Hadaschik, Boris A. ;
Giesel, Frederik L. ;
Debus, Juergen ;
Haberkorn, Uwe .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2014, 41 (01) :11-20
[5]  
Akgun Z, 2005, J LABELLED COMPD RAD, V48, pS299
[6]  
ALBERTO R, 1992, APPL RADIAT ISOTOPES, V43, P869
[7]   Copper-64 Radiopharmaceuticals for PET Imaging of Cancer: Advances in Preclinical and Clinical Research [J].
Anderson, Carolyn J. ;
Ferdani, Riccardo .
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2009, 24 (04) :379-393
[8]   Samarium lexidronam (153Sm-EDTMP):: skeletal radiation for osteoblastic bone metastases and osteosarcoma [J].
Anderson, Pete ;
Nunez, Rodolfo .
EXPERT REVIEW OF ANTICANCER THERAPY, 2007, 7 (11) :1517-1527
[9]   Optimising the radiolabelling properties of technetium tricarbonyl and His-tagged proteins [J].
Badar, Adam ;
Williams, Jennifer ;
de Rosales, Rafael T. M. ;
Tavare, Richard ;
Kampmeier, Florian ;
Blower, Philip J. ;
Mullen, Gregory E. D. .
EJNMMI RESEARCH, 2014, 4 :1-8
[10]  
Bagunya-Torres J., UNPUB