Screening for cervical cancer: Choices & dilemmas

被引:42
作者
Rajaram, Shalini [1 ,3 ]
Gupta, Bindiya [2 ]
机构
[1] All India Inst Med Sci, Dept Obstet & Gynecol, Rishikesh, Uttarakhand, India
[2] Univ Coll Med Sci & Guru Teg Bahadur Hosp, Delhi, India
[3] AIIMS Rishikesh, Dept Obstet & Gynecol, Veerbhadra Rd, Rishikesh 249203, Uttaranchal, India
关键词
Biomarker; cervical cancer screening; cervical cytology; DNA methylation; HPV DNA testing; p16/Ki 67 dual staining; VIA; HUMAN-PAPILLOMAVIRUS DNA; HPV-POSITIVE WOMEN; LIQUID-BASED CYTOLOGY; EXTENDED FOLLOW-UP; CLINICAL-PERFORMANCE; VISUAL INSPECTION; ACETIC-ACID; INTRAEPITHELIAL NEOPLASIA; BASE-LINE; RISK;
D O I
10.4103/ijmr.IJMR_857_20
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Cervical cancer is the fourth most common cancer in women in the world. To eliminate cervical cancer by 2030, the World Health Organization has given the target of 70 per cent coverage of twice lifetime screening. A multitude of screening methods are available, including cytology, human papillomavirus (HPV) DNA testing and visual inspection tests. Precision tests, including molecular and protein biomarkers such as DNA methylation, p16 immunostaining, and HPV mRNA testing help to enhance specificity of the screening. Worldwide HPV DNA testing with or without cytology is used as a screening method of choice, while in resource-poor settings, visual inspection tests are recommended. The major hurdle is a uniform and systematic implementation with a recall method in the population. Besides, controversies still exist regarding strategies to manage HPV-positive women and developing guidelines to screen the vaccinated population.
引用
收藏
页码:210 / 220
页数:11
相关论文
共 79 条
[1]   Implementing community-based cervical cancer screening programs using visual inspection with acetic acid in India: A systematic review [J].
Adsul, Prajakta ;
Manjunath, Nitin ;
Srinivas, Vijaya ;
Arun, Anjali ;
Madhivanan, Purnima .
CANCER EPIDEMIOLOGY, 2017, 49 :161-174
[2]  
[Anonymous], CERVICAL CANC SCREEN
[3]   Pooled analysis of the accuracy of five cervical cancer screening tests assessed in eleven studies in Africa and India [J].
Arbyn, Marc ;
Sankaranarayanan, Rengaswamy ;
Muwonge, Richard ;
Keita, Namory ;
Dolo, Amadou ;
Mbalawa, Charles Gombe ;
Nouhou, Hassan ;
Sakande, Boblewende ;
Wesley, Ramani ;
Somanathan, Thara ;
Sharma, Anjali ;
Shastri, Surendra ;
Basu, Parthasarathy .
INTERNATIONAL JOURNAL OF CANCER, 2008, 123 (01) :153-160
[4]   The APTIMA HPV assay versus the hybrid capture 2 test in triage of women with ASC-US or LSIL cervical cytology: A meta-analysis of the diagnostic accuracy [J].
Arbyn, Marc ;
Roelens, Jolien ;
Cuschieri, Kate ;
Cuzick, Jack ;
Szarewski, Ann ;
Ratnam, Sam ;
Reuschenbach, Miriam ;
Belinson, Suzanne ;
Belinson, Jerome L. ;
Monsonego, Joseph .
INTERNATIONAL JOURNAL OF CANCER, 2013, 132 (01) :101-108
[5]   Early Impact of Human Papillomavirus Vaccination on Cervical NeoplasiauNationwide Follow-up of Young Danish Women [J].
Baldur-Felskov, Birgitte ;
Dehlendorff, Christian ;
Munk, Christian ;
Kjaer, Susanne K. .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2014, 106 (03)
[6]   Management algorithms for cervical cancer screening and precancer treatment for resource-limited settings [J].
Basu, Partha ;
Meheus, Filip ;
Chami, Youssef ;
Hariprasad, Roopa ;
Zhao, Fanghui ;
Sankaranarayanan, Rengaswamy .
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2017, 138 :26-32
[7]   Can human papillomavirus DNA testing of self-collected vaginal samples compare with physician-collected cervical samples and cytology for cervical cancer screening in developing countries? [J].
Bhatla, Neerja ;
Dar, Lalit ;
Patro, A. Rajkumar ;
Kumar, Pankaj ;
Kriplani, Alka ;
Gulati, Arti ;
Iyer, Venkateswaran K. ;
Mathur, Sandeep R. ;
Sreenivas, Vishnubhatla ;
Shah, Keerti V. ;
Gravitt, Patti E. .
CANCER EPIDEMIOLOGY, 2009, 33 (06) :446-450
[8]   Screening and management of preinvasive lesions of the cervix: Good clinical practice recommendations from the Federation of Obstetrics and Gynaecologic Societies of India (FOGSI) [J].
Bhatla, Neerja ;
Singhal, Seema ;
Saraiya, Usha ;
Srivastava, Shikha ;
Bhalerao, Sarita ;
Shamsunder, Saritha ;
Chavan, Niranjan ;
Basu, Partha ;
Purandare, C. N. ;
Agarwal, P. ;
Arora, M. ;
Bhatla, N. ;
Basu, P. ;
Bhalerao, S. ;
Batra, S. ;
Banerjee, D. ;
Chavan, N. ;
Dhorepatil, B. ;
Gupta, B. ;
Gandhi, G. ;
Gupta, K. ;
Ganesh, P. ;
Joshi, S. ;
Kriplani, A. ;
Khanna, R. ;
Kumar, S. ;
Maheshwari, A. ;
Meena, J. ;
Nayak, B. ;
Natarajan, J. ;
Pai, R. ;
Pathak, R. ;
Prabhu, R. B. ;
Peedicayil, A. ;
Rajaram, S. ;
Sekhon, R. ;
Shamsunder, S. ;
Srivastava, S. ;
Singh, U. ;
Singhal, S. ;
Saraiya, U. ;
Zutshi, V. .
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2020, 46 (02) :201-214
[9]   Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries [J].
Brisson, Marc ;
Kim, Jane J. ;
Canfell, Karen ;
Drolet, Melanie ;
Gingras, Guillaume ;
Burger, Emily A. ;
Martin, Dave ;
Simms, Kate T. ;
Benard, Elodie ;
Boily, Marie-Claude ;
Sy, Stephen ;
Regan, Catherine ;
Keane, Adam ;
Caruana, Michael ;
Nguyen, Diep T. N. ;
Smith, Megan A. ;
Laprise, Jean-Francois ;
Jit, Mark ;
Alary, Michel ;
Bray, Freddie ;
Fidarova, Elena ;
Elsheikh, Fayad ;
Bloem, Paul J. N. ;
Broutet, Nathalie ;
Hutubessy, Raymond .
LANCET, 2020, 395 (10224) :575-590
[10]   Global elimination of cervical cancer as a public health problem [J].
Brisson, Marc ;
Drolet, Melanie .
LANCET ONCOLOGY, 2019, 20 (03) :319-321