A "reductionist" view of cardiomyopathy

被引：33

作者：

Dimmeler, Stefanie ^{[1
]}

Zeiher, Andreas M. ^{[1
]}

机构：

[1] Univ Frankfurt, Dept Internal Med 3, D-6000 Frankfurt, Germany

来源：

CELL | 2007年 / 130卷 / 03期

关键词：

D O I：

10.1016/j.cell.2007.07.028

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Oxidative stress due to the generation of reactive oxygen species has been implicated in many diseases. Rajasekaran et al. ( 2007) now make the surprising discovery that its counterpart "reductive stress," caused by an increase in reduced glutathione, contributes to cardiomyopathy triggered by protein aggregation.

引用

页码：401 / 402

页数：2

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