A phase 2, randomized, placebo-controlled, double-blind, ascending dose study to evaluate efficacy, safety, tolerability, pharmacokinetics, pharmacodynamics & pharmacogenetics of CC-220 in subjects with SLE

被引：0
|
作者：
Werth, V. [1 ]
Furie, R. [2 ]
Hough, D. [3 ]
Korish, S. [3 ]
Weiswasser, M. [3 ]
Azarian, A. [3 ]
Schafer, P. [3 ]
Delev, N. [3 ]
Choi, S. [3 ]
机构：
[1] UPenn, Philadelphia, PA USA
[2] Northwell Hlth, Great Neck, NY USA
[3] Celgene, Summit, NJ USA
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2017年 / 137卷 / 05期
关键词：
D O I：
10.1016/j.jid.2017.02.396
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
379
引用
收藏
页码：S65 / S65
页数：1
相关论文
共 50 条
  • [41] Safety, tolerability, and pharmacokinetics of oral baicalein tablets in healthy Chinese subjects: A single-center, randomized, double-blind, placebo-controlled multiple-ascending-dose study
    Li, Lijun
    Gao, Hongzhi
    Lou, Kun
    Luo, Hongmei
    Hao, Sheng
    Yuan, Jing
    Liu, Zeyuan
    Dong, Ruihua
    CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2021, 14 (05): : 2017 - 2024
  • [42] Correction to: A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Dose, and Food Effect Trial of the Safety, Tolerability and Pharmacokinetics of Highly Purified Cannabidiol in Healthy Subjects
    Lesley Taylor
    Barry Gidal
    Graham Blakey
    Bola Tayo
    Gilmour Morrison
    CNS Drugs, 2019, 33 : 397 - 397
  • [43] A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Dose, Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BIIB023 (Anti-TWEAK) in Subjects with Rheumatoid Arthritis
    Wisniacki, Nicolas
    Chindalore, Vishala L.
    Codding, Christine E.
    Greenwald, Maria W.
    Shaw, Marianne L.
    Fitilev, Sergey
    Ershova, Olga
    Hu, Xiao
    Zheng, Timothy S.
    Amaravadi, Lakshmi
    Zhang, Ray
    Burkly, Linda C.
    ARTHRITIS AND RHEUMATISM, 2011, 63 (10): : S858 - S858
  • [44] Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study
    Valérie Bourdès
    Peter Dogterom
    André Aleman
    Pierre Parmantier
    Damien Colas
    Sighild Lemarchant
    Sébastien Marie
    Thomas Chou
    Khalid Abd-Elaziz
    Yann Godfrin
    Neurology and Therapy, 2022, 11 : 1353 - 1374
  • [45] Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study
    Bourdes, Valerie
    Dogterom, Peter
    Aleman, Andre
    Parmantier, Pierre
    Colas, Damien
    Lemarchant, Sighild
    Marie, Sebastien
    Chou, Thomas
    Abd-Elaziz, Khalid
    Godfrin, Yann
    NEUROLOGY AND THERAPY, 2022, 11 (03) : 1353 - 1374
  • [46] A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety, and Tolerability of Prucalopride in Men With Chronic Constipation
    Yiannakou, Yan
    Piessevaux, Hubert
    Bouchoucha, Michel
    Schiefke, Ingolf
    Filip, Rafal
    Gabalec, Libor
    Dina, Ion
    Stephenson, David
    Kerstens, Rene
    Etherson, Kevin
    Levine, Amy
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2015, 110 (05): : 741 - 748
  • [47] A phase I, double-blind, placebo-controlled, dose-escalation study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of inhaled APN01
    Bauer, Martin
    Jorda, Anselm
    Woelfl-Duchek, Michael
    Bergmann, Felix
    Nussbaumer-Proell, Alina
    Steindl, Ariane
    Gugenberger, Romana
    Bischof, Sarah
    Wimmer, Doris
    Idzko, Marco
    Zeitlinger, Markus
    BRITISH JOURNAL OF PHARMACOLOGY, 2023, 180 : 233 - 233
  • [48] A single-center, randomized, placebo-controlled, double-blind study to evaluate the safety, tolerability, and pharmacokinetics of multiple-ascending doses of pridopidine in healthy volunteers
    Osterberg, O.
    Ivkovic, J.
    Sundgreen, C.
    Muglia, P.
    Prang, A.
    Darpo, B.
    NEUROTHERAPEUTICS, 2013, 10 (01) : 175 - 175
  • [49] Safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of aficamten in healthy Chinese participants: a randomized, double-blind, placebo-controlled, phase 1 study
    Zhao, Xue
    Liu, Hongzhong
    Tian, Wei
    Fang, Ligang
    Yu, Mengyang
    Wu, Xiaofei
    Liu, Aijing
    Wan, Ruijie
    Li, Li
    Luo, Jinghui
    Li, Yuqiong
    Liu, Bo
    He, Yu
    Chen, Xiaowen
    Li, Yuan
    Xu, Donghong
    Wang, Hongyun
    Han, Xiaohong
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [50] Safety, Tolerability and Pharmacokinetics of Dalcetrapib Following Single and Multiple Ascending Doses in Healthy SubjectsA Randomized, Double-Blind, Placebo-Controlled, Phase I Study
    Michael Derks
    Judith Anzures-Cabrera
    Lynn Turnbull
    Mary Phelan
    Clinical Drug Investigation, 2011, 31 : 325 - 335
12345