Management of Acquired Bleeding Problems in Cancer Patients

被引:2
作者
DeLoughery, Thomas G. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Oregon Hlth & Sci Univ, Dept Med, Div Hematol, Portland, OR 97201 USA
[2] Oregon Hlth & Sci Univ, Dept Med, Div Med Oncol, Portland, OR 97201 USA
[3] Oregon Hlth & Sci Univ, Dept Pathol, Div Lab Med, Portland, OR 97201 USA
[4] Oregon Hlth & Sci Univ, Dept Pediat, Div Hematol, Portland, OR 97201 USA
[5] Oregon Hlth & Sci Univ, Dept Pediat, Div Med Oncol, Portland, OR 97201 USA
关键词
Bleeding; Cancer; Leukemia; Myeloma; Amyloid; Disseminated intravascular coagulation; THROMBOTIC THROMBOCYTOPENIC PURPURA; HEMOLYTIC-UREMIC SYNDROME; BONE-MARROW TRANSPLANTATION; RECOMBINANT FACTOR-VIIA; HEPARIN-INDUCED THROMBOCYTOPENIA; DISSEMINATED INTRAVASCULAR COAGULATION; ACUTE MYOCARDIAL-INFARCTION; OF-AMERICAN-PATHOLOGISTS; VON-WILLEBRAND-SYNDROME; ACTIVATED FACTOR-VII;
D O I
10.1016/j.hoc.2010.03.008
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cancer patients can have acquired bleeding problems for many reasons. In this review, an approach to the evaluation and management of the bleeding patient is discussed. Specific issues including coagulation defects, thrombocytopenia, platelet dysfunction, and bleeding complications of specific hematological malignancies due to anticoagulation, are discussed.
引用
收藏
页码:603 / +
页数:23
相关论文
共 117 条
  • [1] Recombinant factor VIIa: review of efficacy, dosing regimens and safety in patients with congenital and acquired factor VIII or IX inhibitors
    Abshire, T
    Kenet, G
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2004, 2 (06) : 899 - 909
  • [2] Treatment of warfarin-associated intracerebral hemorrhage:: Literature review and expert opinion
    Aguilar, Maria I.
    Hart, Robert G.
    Kase, Carlos S.
    Freeman, William D.
    Hoeben, Maj Barbara J.
    Garcia, Rosa C.
    Ansell, Jack E.
    Mayer, Stephan A.
    Norrving, Bo
    Rosand, Jonathan
    Steiner, Thorsten
    Wijdicks, Eelco F. M.
    Yamaguchi, Takenori
    Yasaka, Masahiro
    [J]. MAYO CLINIC PROCEEDINGS, 2007, 82 (01) : 82 - 92
  • [3] UREMIA AS A CAUSE OF BLEEDING
    ANDRASSY, K
    RITZ, E
    [J]. AMERICAN JOURNAL OF NEPHROLOGY, 1985, 5 (05) : 313 - 319
  • [4] Haemostatic problems in acute promyelocytic leukaemia
    Arbuthnot, Carolina
    Wilde, Jonathan T.
    [J]. BLOOD REVIEWS, 2006, 20 (06) : 289 - 297
  • [5] Current concepts - Drug-induced immune thrombocytopenia
    Aster, Richard H.
    Bougie, Daniel W.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (06) : 580 - 587
  • [6] Current management of acquired factor VIII inhibitors
    Barnett, Brian
    Kruse-Jarres, Rebecca
    Leissinger, Cindy A.
    [J]. CURRENT OPINION IN HEMATOLOGY, 2008, 15 (05) : 451 - 455
  • [7] IMPROVED SURVIVAL IN THROMBOTIC THROMBOCYTOPENIC PURPURA HEMOLYTIC UREMIC SYNDROME - CLINICAL-EXPERIENCE IN 108 PATIENTS
    BELL, WR
    BRAINE, HG
    NESS, PM
    KICKLER, TS
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (06) : 398 - 403
  • [8] Occurrence and clinical significance of thrombocytopenia in a population undergoing high-risk percutaneous coronary revascularization
    Berkowitz, SD
    Sane, DC
    Sigmon, KN
    Shavender, JH
    Harrington, RA
    Tcheng, JE
    Topol, EJ
    Califf, RM
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1998, 32 (02) : 311 - 319
  • [9] Berkowitz SD, 1997, CIRCULATION, V95, P809
  • [10] Evidence for the use of recombinant factor VIIa in the prevention and treatment of bleeding in patients without hemophilia
    Birchall, Janet
    Stanworth, Simon J.
    Duffy, Michael R.
    Doree, Carolyn J.
    Hyde, Christopher
    [J]. TRANSFUSION MEDICINE REVIEWS, 2008, 22 (03) : 177 - 187