C1 inhibitor deficiency in a patient with rheumatoid arthritis - Increased risk of adverse effects of penicillamine?

被引:0
|
作者
Sturfelt, G
Rydgren, L
Truedsson, L
Alm, P
Sjoholm, AG
机构
[1] UNIV LUND HOSP,DEPT MED MICROBIOL,S-22185 LUND,SWEDEN
[2] UNIV LUND HOSP,DEPT PATHOL,S-22185 LUND,SWEDEN
关键词
C1; inhibitor; hereditary angioedema; complement deficiency; rheumatoid arthritis; D-penicillamine;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report the coincidence of hereditary angioedema and rheumatoid arthritis in a male patient and in his father. During treatment with D-penicillamine the patient developed a transient lupus-like disorder with glomerulonephritis that resolved when D-penicillamine was discontinued. He later was diagnosed with malignant lymphoma. Impaired classical complement pathway function could have contributed to development of the drug reaction.
引用
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页码:378 / 381
页数:4
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