The role of iron repletion in adult iron deficiency anemia and other diseases

被引：113

作者：

Elstrott, Benjamin ^{[1
]}

Khan, Lubna ^{[1
]}

Olson, Sven ^{[1
,2
]}

Raghunathan, Vikram ^{[1
]}

DeLoughery, Thomas ^{[1
]}

Shatzel, Joseph J. ^{[1
,2
]}

机构：

[1] Oregon Hlth & Sci Univ, Knight Canc Inst, Div Hematol Med Oncol, Portland, OR 97201 USA

[2] Oregon Hlth & Sci Univ, Dept Biomed Engn, Portland, OR 97201 USA

来源：

EUROPEAN JOURNAL OF HAEMATOLOGY | 2020年 / 104卷 / 03期

关键词：

anemia; hematopathology; iron deficiency; iron repletion; CLINICAL-PRACTICE GUIDELINES; INFLAMMATORY-BOWEL-DISEASE; CHRONIC KIDNEY-DISEASE; INTRAVENOUS IRON; FERRIC CARBOXYMALTOSE; ORAL IRON; BARIATRIC SURGERY; HEART-FAILURE; MANAGEMENT; ABSORPTION;

D O I：

10.1111/ejh.13345

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Iron deficiency anemia (IDA) is the most prevalent and treatable form of anemia worldwide. The clinical management of patients with IDA requires a comprehensive understanding of the many etiologies that can lead to iron deficiency including pregnancy, blood loss, renal disease, heavy menstrual bleeding, inflammatory bowel disease, bariatric surgery, or extremely rare genetic disorders. The treatment landscape for many causes of IDA is currently shifting toward more abundant use of intravenous (IV) iron due to its effectiveness and improved formulations that decrease the likelihood of adverse effects. IV iron has found applications beyond treatment of IDA, and there is accruing data about its efficacy in patients with heart failure, restless leg syndrome, fatigue, and prevention of acute mountain sickness. This review provides a framework to diagnose, manage, and treat patients presenting with IDA and discusses other conditions that benefit from iron supplementation.

引用

页码：153 / 161

页数：9

共 96 条

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