SARS-CoV-2 (COVID-19): Beginning to Understand a New Virus

被引：11
作者：
Van Vo, Giau [1 ,2 ,3 ]
Bagyinszky, Eva [1 ,2 ]
Park, Yoon Soo [4 ]
Hulme, John [2 ]
An, Seong Soo A. [2 ]
机构：
[1] Gachon Univ, Grad Sch Environm, Dept Ind & Environm Engn, Seongnam Si, Gyeonggi Do, South Korea
[2] Gachon Univ, Dept Bionanotechnol, Seongnam Si, Gyeonggi Do, South Korea
[3] Vietnam Natl Univ Ho Chi Minh City, Sch Med, Ho Chi Minh City, Vietnam
[4] Yonsei Univ, Yongin Severance Hosp, Coll Med, Dept Internal Med, Yongin, Gyeonggi Do, South Korea
来源：
CLINICAL, BIOLOGICAL AND MOLECULAR ASPECTS OF COVID-19 | 2021年 / 1321卷
基金：
新加坡国家研究基金会;
关键词：
COVID-19; SARS-CoV-2; Semen; Wuhan; Coronavirus; SARS CORONAVIRUS; SPIKE PROTEIN; ACE2; RECEPTOR; PNEUMONIA; TRANSMISSION; CHLOROQUINE; INFECTION; 2019-NCOV; BINDING; EBOLA;
D O I：
10.1007/978-3-030-59261-5_1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Within the last two decades, several members of the Coronaviridae family demonstrated epidemic potential. In late 2019, an unnamed genetic relative, later named SARS-CoV-2 (COVID-19), erupted in the highly populous neighborhoods of Wuhan, China. Unchecked, COVID-19 spread rapidly among interconnected communities and related households before containment measures could be enacted. At present, the mortality rate of COVID-19 infection worldwide is 6.6%. In order to mitigate the number of infections, restrictions or recommendations on the number of people that can gather in a given area have been employed by governments worldwide. For governments to confidently lift these restrictions as well as counter a potential secondary wave of infections, alternative medications and diagnostic strategies against COVID-19 are urgently required. This review has focused on these issues.
引用
收藏
页码：3 / 19
页数：17
相关论文
共 102 条
  • [1] Immune Responses to Influenza Virus and Its Correlation to Age and Inherited Factors
    Bahadoran, Azadeh
    Lee, Sau H.
    Wang, Seok M.
    Manikam, Rishya
    Rajarajeswaran, Jayakumar
    Raju, Chandramathi S.
    Sekaran, Shamala D.
    [J]. FRONTIERS IN MICROBIOLOGY, 2016, 7
  • [2] Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection
    Balachandran, S
    Roberts, PC
    Brown, LE
    Truong, H
    Pattnaik, AK
    Archer, DR
    Barber, GN
    [J]. IMMUNITY, 2000, 13 (01) : 129 - 141
  • [3] Teicoplanin: an alternative drug for the treatment of COVID-19?
    Baron, Sophie Alexandra
    Devaux, Christian
    Colson, Philippe
    Raoult, Didier
    Rolain, Jean-Marc
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2020, 55 (04)
  • [4] Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk
    Breban, Romulus
    Riou, Julien
    Fontanet, Arnaud
    [J]. LANCET, 2013, 382 (9893) : 694 - 699
  • [5] Use of a new RNA next generation sequencing approach for the specific detection of virus infection in cells
    Brussel, Audrey
    Brack, Kerstin
    Muth, Erika
    Zirwes, Rudolf
    Cheval, Justine
    Hebert, Charles
    Charpin, Jean-Marie
    Marinaci, Alice
    Flan, Benoit
    Ruppach, Horst
    Beurdeley, Pascale
    Eloit, Marc
    [J]. BIOLOGICALS, 2019, 59 : 29 - 36
  • [6] The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
    Caly, Leon
    Druce, Julian D.
    Catton, Mike G.
    Jans, David A.
    Wagstaff, Kylie M.
    [J]. ANTIVIRAL RESEARCH, 2020, 178
  • [7] Angiotensin-converting enzyme 2 as a therapeutic target for heart failure
    Chamsi-Pasha M.A.R.
    Shao Z.
    Tang W.H.W.
    [J]. Current Heart Failure Reports, 2014, 11 (1) : 58 - 63
  • [8] A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
    Chan, Jasper Fuk-Woo
    Yuan, Shuofeng
    Kok, Kin-Hang
    To, Kelvin Kai-Wang
    Chu, Hin
    Yang, Jin
    Xing, Fanfan
    Liu, Jieling
    Yip, Cyril Chik-Yan
    Poon, Rosana Wing-Shan
    Tsoi, Hoi-Wah
    Lo, Simon Kam-Fai
    Chan, Kwok-Hung
    Poon, Vincent Kwok-Man
    Chan, Wan-Mui
    Ip, Jonathan Daniel
    Cai, Jian-Piao
    Cheng, Vincent Chi-Chung
    Chen, Honglin
    Hui, Christopher Kim-Ming
    Yuen, Kwok-Yung
    [J]. LANCET, 2020, 395 (10223) : 514 - 523
  • [9] IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes
    Channappanavar, Rudragouda
    Fehr, Anthony R.
    Zheng, Jian
    Wohlford-Lenane, Christine
    Abrahante, Juan E.
    Mack, Matthias
    Sompallae, Ramakrishna
    McCray, Paul B., Jr.
    Meyerholz, David K.
    Perlman, Stanley
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2019, 129 (09) : 3625 - 3639
  • [10] Update on the angiotensin converting enzyme 2-angiotensin (1-7)-Mas receptor axis: fetal programing, sex differences, and intracellular pathways
    Chappell, Mark C.
    Marshall, Allyson C.
    Alzayadneh, Ebaa M.
    Shaltoutz, Hossam A.
    Diz, Debra I.
    [J]. FRONTIERS IN ENDOCRINOLOGY, 2014, 5
12345678910