Clinical Trials of Pharmacological Therapies in Acute Heart Failure Syndromes Lessons Learned and Directions Forward

被引：116

作者：

Felker, G. Michael ^{[2
]}

Pang, Peter S. ^{[3
]}

Adams, Kirkwood F. ^{[4
,5
]}

Cleland, John G. F. ^{[6
]}

Cotter, Gad ^{[7
]}

Dickstein, Kenneth ^{[8
]}

Filippatos, Gerasimos S. ^{[9
]}

Fonarow, Gregg C. ^{[10
]}

Greenberg, Barry H. ^{[11
]}

Hernandez, Adrian F. ^{[12
]}

Khan, Sadiya

Komajda, Michel ^{[13
]}

Konstam, Marvin A. ^{[14
,15
]}

Liu, Peter P. ^{[16
]}

Maggioni, Aldo P. ^{[17
]}

Massie, Barry M. ^{[18
]}

McMurray, John J. ^{[19
]}

Mehra, Mandeep ^{[20
]}

Metra, Marco ^{[21
]}

O'Connell, John ^{[22
]}

O'Connor, Christopher M. ^{[23
]}

Pina, Ileana L. ^{[24
]}

Ponikowski, Piotr ^{[25
]}

Sabbah, Hani N. ^{[26
]}

Teerlink, John R. ^{[27
]}

Udelson, James E. ^{[28
]}

Yancy, Clyde W. ^{[29
]}

Zannad, Faiez ^{[30
]}

Gheorghiade, Mihai ^{[1
]}

机构：

[1] Northwestern Univ, Ctr Cardiovasc Qual & Outcomes, Feinberg Sch Med, Dept Med, 645 N Michigan Ave,Suite 1006, Chicago, IL 60611 USA

[2] Duke Clin Res Inst Durham, Durham, NC USA

[3] Northwestern Univ, Ctr Cardiovasc Qual & Outcomes, Feinberg Sch Med, Dept Emergency Med, Chicago, IL 60611 USA

[4] Univ N Carolina, Sch Med, Dept Med, Chapel Hill, NC USA

[5] Univ N Carolina, Sch Med, Dept Radiol, Chapel Hill, NC 27514 USA

[6] Univ Hull, Dept Cardiol, Castle Hill Hosp, Kingston Upon Hull, Yorks, England

[7] Momentum Res Inc, Durham, NC USA

[8] Univ Bergen, Inst Internal Med, Bergen, Norway

[9] Univ Athens, Hosp Attikon, Athens, Greece

[10] David Geffen UCLA, Med Ctr, Ahmanson UCLA Cardiomyopathy Ctr, Los Angeles, CA USA

[11] Univ Calif San Diego, San Diego, CA 92103 USA

[12] Duke Univ, Sch Med, Duke Clin Res Inst, Durham, NC USA

[13] Univ Paris 06, AP HP, Paris, France

[14] Tufts Med Ctr, Ctr Cardiovasc, Boston, MA USA

[15] Tufts Univ, Sch Med, Boston, MA 02111 USA

[16] Univ Toronto, Toronto Gen Hosp, Inst Circulatory & Resp Hlth, Canadian Inst Hlth, Toronto, ON M5S 1A1, Canada

[17] ANMCO Res Ctr, Florence, Italy

[18] Univ Calif San Francisco, Div Cardiol, San Francisco Vet Affairs Med Ctr, San Francisco, CA 94143 USA

[19] Univ Glasgow, BHF Cardiovasc Res Ctr, Glasgow, Lanark, Scotland

[20] Univ Maryland, Sch Med, Baltimore, MD 21201 USA

[21] Univ & Civil Hosp Brescia, Dept Expt & Appl Med, Brescia, Italy

[22] Feinberg Sch Med, Div Cardiol, Chicago, IL USA

[23] Duke Univ, Med Ctr, Duke Heart Ctr, Div Clin Pharmacol, Durham, NC 27710 USA

[24] Case Western Reserve Univ, Cleveland, OH 44106 USA

[25] Med Univ, Fac Hlth Sci, Clin Mil Hosp, Wroclaw, Poland

[26] Henry Ford Hosp, Dept Med, Detroit, MI 48202 USA

[27] Vet Affairs Med Ctr, San Francisco, CA 94121 USA

[28] Tufts Med Ctr, Div Cardiol, Boston, MA USA

[29] Baylor Heart & Vasc Inst, Dallas, TX USA

[30] Nancy Univ, Dept Cardiol, Nancy, France

来源：

CIRCULATION-HEART FAILURE | 2010年 / 3卷 / 02期

关键词：

heart failure; patients; trials; acute heart failure; WORSENING RENAL-FUNCTION; IN-HOSPITAL MORTALITY; RANDOMIZED CONTROLLED-TRIALS; CARDIAC TROPONIN-I; END-POINTS; MYOCARDIAL-INFARCTION; RISK STRATIFICATION; FLUID ACCUMULATION; PROGNOSTIC VALUE; OUTCOMES;

D O I：

10.1161/CIRCHEARTFAILURE.109.893222

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：314 / 325

页数：12

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