Functionalized gold nanoparticles for drug delivery

被引：388
作者：
Han, Gang [1 ]
Ghosh, Partha [1 ]
Rotello, Vincent M. [1 ]
机构：
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
来源：
NANOMEDICINE | 2007年 / 2卷 / 01期
关键词：
delivery; DNA; drug; gene; glutathione; gold; nanoparticles; photochemistry; release;
D O I：
10.2217/17435889.2.1.113
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Functionalized gold nanoparticles represent highly attractive and promising candidates in the applications of drug delivery owing to their unique dimensions, tunable functionalities on the surface and controllable drug release. This review illustrates the recent advances in the field of drug delivery using gold nanoparticles as carriers for therapeutic agents.
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收藏
页码：113 / 123
页数：11
相关论文
共 40 条
[21]   Inhibition of DNA transcription using cationic mixed monolayer protected gold clusters [J].
McIntosh, CM ;
Esposito, EA ;
Boal, AK ;
Simard, JM ;
Martin, CT ;
Rotello, VM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (31) :7626-7629
[22]   HUMAN GENE-THERAPY COMES OF AGE [J].
MILLER, AD .
NATURE, 1992, 357 (6378) :455-460
[23]   Colloidal gold: A novel nanoparticle vector for tumor directed drug delivery [J].
Paciotti, GF ;
Myer, L ;
Weinreich, D ;
Goia, D ;
Pavel, N ;
McLaughlin, RE ;
Tamarkin, L .
DRUG DELIVERY, 2004, 11 (03) :169-183
[24]   Colloidal gold nanoparticles: A novel nanoparticle platform for developing multifunctional tumor-targeted drug delivery vectors [J].
Paciotti, Giulio F. ;
Kingston, David G. I. ;
Tamarkin, Lawrence .
DRUG DEVELOPMENT RESEARCH, 2006, 67 (01) :47-54
[25]   Acid- and salt-triggered multifunctional poly(propylene imine) dendrimer as a prospective drug delivery system [J].
Paleos, CM ;
Tsiourvas, D ;
Sideratou, Z ;
Tziveleka, L .
BIOMACROMOLECULES, 2004, 5 (02) :524-529
[26]  
Rosi NL, 2006, SCIENCE, V312, P1027, DOI 10.1126/science.1125559
[27]   Nanostructures in biodiagnostics [J].
Rosi, NL ;
Mirkin, CA .
CHEMICAL REVIEWS, 2005, 105 (04) :1547-1562
[28]   Synthesis of nitric oxide-releasing gold nanoparticles [J].
Rothrock, AR ;
Donkers, RL ;
Schoenfisch, MH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (26) :9362-9363
[29]   Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities [J].
Saito, G ;
Swanson, JA ;
Lee, KD .
ADVANCED DRUG DELIVERY REVIEWS, 2003, 55 (02) :199-215
[30]   Multifunctional nanorods for gene delivery [J].
Salem, AK ;
Searson, PC ;
Leong, KW .
NATURE MATERIALS, 2003, 2 (10) :668-671
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