A novel one pot synthesis of 2-dimethylaminoquinoline derivatives from arylazido ketones by cyclization under Vilsmeier condition

被引：10

作者：

Amaresh, RR ^{[1
]}

Perumal, PT ^{[1
]}

机构：

[1] Cent Leather Res Inst, Div Organ Chem, Adyar 600020, Chennai, India

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(98)00625-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-(2-Azidophenyl)ethanone on treatment with Vilsmeier reagent yields 4-chloro-2-dimethylamino-3-quinolinecarboxaldehyde and 4-chloro-2-dimethylaminoquinoline, whereas 1-(2-azidophenyl)propanone and butanone derivatives give the corresponding 4-chloro-3-alkyl-2-dimethylaminoquinolines and 3-alkyl-4-chloroquinolines. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3837 / 3840

页数：4

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