IL-17, now an important target for treatment in arthritis!

被引：4
作者：
Miossec, Pierre [1 ]
机构：
[1] Univ Lyon, Dept Immunol & Rheumatol, Immunogen & Inflammat Res, Unit EA 4130,Edouard Herriot Hosp, 5 Pl Arsonval, F-69437 Lyon, France
来源：
JOINT BONE SPINE | 2017年 / 84卷 / 03期
关键词：
IL-17; Cytokines; Inflammation; Bone resorption; ArthritisIn; RHEUMATOID-ARTHRITIS; CHRONIC INFLAMMATION; CELLS; INTERLEUKIN-17; SYNOVIOCYTES; SECUKINUMAB; CYTOKINE; SYNOVIUM; ALPHA; BONE;
D O I：
10.1016/j.jbspin.2016.12.001
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：247 / 249
页数：3
相关论文
共 21 条
[1]   Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis [J].
Baeten, Dominique ;
Sieper, Joachim ;
Braun, Juergen ;
Baraliakos, Xenofon ;
Dougados, Maxime ;
Emery, Paul ;
Deodhar, Atul ;
Porter, Brian ;
Martin, Ruvie ;
Andersson, Mats ;
Mpofu, Shephard ;
Richards, Hanno B. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (26) :2534-2548
[2]   Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis [J].
Bartok, Beatrix ;
Firestein, Gary S. .
IMMUNOLOGICAL REVIEWS, 2010, 233 :233-255
[3]   IL-17 in Chronic Inflammation: From Discovery to Targeting [J].
Beringer, Audrey ;
Noack, Melissa ;
Miossec, Pierre .
TRENDS IN MOLECULAR MEDICINE, 2016, 22 (03) :230-241
[4]  
Chabaud M, 1999, ARTHRITIS RHEUM-US, V42, P963, DOI 10.1002/1529-0131(199905)42:5<963::AID-ANR15>3.0.CO
[5]  
2-E
[6]   IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis [J].
Chabaud, M ;
Lubberts, E ;
Joosten, L ;
van den Berg, W ;
Miossec, P .
ARTHRITIS RESEARCH, 2001, 3 (03) :168-177
[7]  
Chabaud M, 2001, ARTHRITIS RHEUM, V44, P1293, DOI 10.1002/1529-0131(200106)44:6<1293::AID-ART221>3.0.CO
[8]  
2-T
[9]   IL-17RA Is Essential for Optimal Localization of Follicular Th Cells in the Germinal Center Light Zone To Promote Autoantibody-Producing B Cells [J].
Ding, Yanna ;
Li, Jun ;
Wu, Qi ;
Yang, Pingar ;
Luo, Bao ;
Xie, Shutao ;
Druey, Kirk M. ;
Zajac, Allan J. ;
Hsu, Hui-Chen ;
Mountz, John D. .
JOURNAL OF IMMUNOLOGY, 2013, 191 (04) :1614-1624
[10]   T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines [J].
Fossiez, F ;
Djossou, O ;
Chomarat, P ;
FloresRomo, L ;
AitYahia, S ;
Maat, C ;
Pin, JJ ;
Garrone, P ;
Garcia, E ;
Saeland, S ;
Blanchard, D ;
Gaillard, C ;
DasMahapatra, B ;
Rouvier, E ;
Golstein, P ;
Banchereau, J ;
Lebecque, S .
JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 183 (06) :2593-2603
123