Three-dimensional computational fluid dynamics (CFD) study of the gas-particle circulation pattern within a fluidized bed granulator: By full factorial design of fluidization velocity and particle size

被引:17
作者
Liu, Huolong [1 ,2 ]
Yoon, Seongkyu [1 ]
Li, Mingzhong [2 ]
机构
[1] Univ Massachusetts, Dept Chem Engn, 1 Univ Ave, Lowell, MA 01850 USA
[2] De Montfort Univ, Sch Pharm, Leicester, Leics, England
关键词
Computational fluid dynamics; fluidization; fluidized bed granulator; full factorial design; gas-particle hydrodynamics; SPRAY GRANULATION; WET GRANULATION; COATING PROCESS; SCALE-UP; SIMULATION; SOLIDS; NUCLEATION; BREAKAGE; TRACKING; FLOW;
D O I
10.1080/07373937.2016.1230628
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
The fluidization velocity and mean particle size were selected to be numerically investigated pertaining to their effects on the gas-particle circulation pattern within a fluidized bed granulator by three-dimensional computational fluid dynamics (CFD) simulation applying an Eulerian-Eulerian two-fluid model. The CFD simulations were designed by full factorial design method and the developed CFD model was experimentally validated. The fluidization process was proved to reach a quasi-steady state. The gas-particle circulation pattern and particle concentration distribution were analyzed based on fluidization velocity and mean particle size. A mathematical model was developed to provide guidance on how to change fluidization level during one experiment.
引用
收藏
页码:1043 / 1058
页数:16
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