New fundamental and applied mechanisms in exercise hemorheology

被引:25
作者
Connes, Philippe [1 ,2 ]
Frank, Suhr [3 ,4 ,5 ]
Martin, Cyril [6 ]
Shin, Sehyun [7 ]
Aufradet, Emeline [6 ]
Sunoo, Sub [8 ]
Klara, Brixius [3 ,5 ]
de Mauverger, Eric Raynaud [9 ]
Romana, Marc [2 ]
Messonnier, Laurent [10 ,11 ]
Kang, Joonku [8 ]
Varlet-Marie, Emmanuelle [9 ]
Feasson, Leonard [10 ,11 ]
Hardy-Dessources, Marie-Dominique [2 ]
Wilhelm, Bloch [3 ,5 ]
Brun, Jean-Frederic [9 ]
机构
[1] Univ Antilles Guyane, Lab ACTES, Dept Physiol, EA 3596, Pointe a Pitre, Guadeloupe, France
[2] Univ Antilles Guyane, INSERM, U763, Pointe a Pitre, France
[3] German Sport Univ Cologne, Dept Mol & Cellular Sport Med, Inst Cardiovasc Res & Sport Med, Cologne, Germany
[4] German Sport Univ Cologne, Inst Training Sci & Sport Informat, Cologne, Germany
[5] German Sport Univ Cologne, German Res Ctr Elite Sport, Cologne, Germany
[6] Univ Lyon 1, CRIS, EA647, F-69365 Lyon, France
[7] Korea Univ, Sch Mech Engn, Seoul, South Korea
[8] Kyung Hee Univ, Coll Phys Educ & Sports Sci, Yongin, Kyungki Do, South Korea
[9] INSERM, ERI 25, F-34000 Montpellier, France
[10] Univ St Etienne, St Etienne, France
[11] Univ Savoie, LPE, EA 4338, Chambery, France
关键词
Exercise; red blood cell deformability; red blood cell NOS; sickle cell trait; hypoxia; SICKLE-CELL TRAIT; NITRIC-OXIDE SYNTHASE; RED-BLOOD-CELLS; ADHESION MOLECULES; PLASMA-LEVELS; SUDDEN-DEATH; RHEOLOGY; HEMOGLOBIN; ERYTHROCYTES; PHYSIOLOGY;
D O I
10.3233/CH-2010-1291
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The present article summarizes recent data presented at the Exercise and Hemorheology symposium during the 15th Conference of the European Society for Clinical Hemorheology and Microcirculation (June 28-July 1, Pontresina, Switzerland, 2009). The review starts with several unresolved paradoxes in exercise hemorheology. Then, we focus on the potential hemorheological and immunological mechanisms involved in the adverse events sometimes reported in exercising sickle cell trait carriers, and the role of habitual physical activity. In a fourth part, new results on the effects of acute hypoxia on blood rheology are presented. Finally, we will discuss recent experimental evidences on the role of exercise on the regulation of nitric oxide synthesizing mechanisms in red blood cell.
引用
收藏
页码:131 / 141
页数:11
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