Executive summary of the 2018 KDIGO Hepatitis C in CKD Guideline: welcoming advances in evaluation and management

被引：57

作者：

Jadoul, Michel ^{[1
]}

Berenguer, Marina C. ^{[2
,3
,4
,5
]}

Doss, Wahid ^{[6
]}

Fabrizi, Fabrizio ^{[7
]}

Izopet, Jacques ^{[8
,9
]}

Jha, Vivekanand ^{[10
,11
]}

Kamar, Nassim ^{[12
,13
,14
,15
]}

Kasiske, Bertram L. ^{[16
,17
]}

Lai, Ching-Lung ^{[18
,19
]}

Morales, Jose M. ^{[20
]}

Patel, Priti R. ^{[21
]}

Po, Stanislas ^{[22
]}

Silva, Marcelo O. ^{[23
,24
]}

Balk, Ethan M. ^{[25
]}

Gordon, Craig E. ^{[26
]}

Earley, Amy ^{[27
]}

Di, Mengyang ^{[25
,28
]}

Martin, Paul ^{[29
]}

机构：

[1] Catholic Univ Louvain, Clin Univ St Luc, Dept Nephrol, Brussels, Belgium

[2] Hosp Univ & Politecn La Fe, Dept Gastroenterol, Hepatol Unit, Valencia, Spain

[3] Hosp Univ & Politecn La Fe, Inst Invest La Fe, Valencia, Spain

[4] CIBERehd, Valencia, Spain

[5] Univ Valencia, Sch Med, Valencia, Spain

[6] Natl Hepatol & Trop Med Res Inst, Cairo, Egypt

[7] Maggiore Hosp & IRCCS Fdn, Div Nephrol, Milan, Italy

[8] Toulouse Univ Hosp, Dept Virol, Hepatitis E Virus Natl Reference Ctr, Toulouse, France

[9] Toulouse Univ Paul Sabatier, Toulouse Purpan Ctr Pathophysiol, INSERM, UMR 1043,CNRS,UMR 5282,CPTP, Toulouse, France

[10] George Inst Global Hlth, New Delhi, India

[11] Univ Oxford, Oxford, England

[12] CHU Rangueil, Dept Nephrol, Toulouse, France

[13] CHU Rangueil, Dept Organ Transplantat, Toulouse, France

[14] CHU Purpan, INSERM, U1043, IFR BMT, Toulouse, France

[15] Univ Paul Sabatier, Toulouse, France

[16] Hennepin Cty Med Ctr, Dept Med, Minneapolis, MN 55415 USA

[17] Minneapolis Med Res Fdn Inc, Sci Registry Transplant Recipients, Minneapolis, MN USA

[18] Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China

[19] Univ Hong Kong, State Key Lab Liver Res, Hong Kong, Hong Kong, Peoples R China

[20] Hosp 12 Octubre, Res Inst, Nephrol Dept, Madrid, Spain

[21] Ctr Dis Control & Prevent, Div Healthcare Qual Promot, Atlanta, GA USA

[22] Univ Paris 05, Hop Cochin, Hepatol Dept, INSERM,U1223,Inst Pasteur, Paris, France

[23] Hosp Univ Austral, Hepatol & Liver Transplant Unit, Buenos Aires, DF, Argentina

[24] LALREAN, Buenos Aires, DF, Argentina

[25] Brown Univ, Sch Publ Hlth, Ctr Evidence Synth Hlth, Providence, RI 02912 USA

[26] Boston Univ, Med Ctr, Renal Sect, Boston, MA USA

[27] Evidera, Waltham, MA USA

[28] Brown Univ, Rhode Isl Hosp, Alpert Med Sch, Providence, RI 02903 USA

[29] Univ Miami, Div Hepatol, Miami, FL USA

来源：

KIDNEY INTERNATIONAL | 2018年 / 94卷 / 04期

关键词：

antivirals; chronic kidney disease; cryoglobulinemia; dialysis; direct-acting antivirals; glomerular diseases; guideline; hemodialysis; hepatitis C virus; infection control; KDIGO; kidney transplantation; liver testing; nosocomial transmission; screening; systematic review;

D O I：

10.1016/j.kint.2018.06.011

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Infection with the hepatitis C virus (HCV) has adverse liver, kidney, and cardiovascular consequences in patients with chronic kidney disease (CKD), including those on dialysis therapy and in those with a kidney transplant. Since the publication of the original Kidney Disease: Improving Global Outcomes (KDIGO) HCV Guideline in 2008, major advances in HCV management, particularly with the advent of direct-acting antiviral therapies, have now made the cure of HCV possible in CKD patients. In addition, diagnostic techniques have evolved to enable the noninvasive diagnosis of liver fibrosis. Therefore, the Work Group undertook a comprehensive review and update of the KDIGO HCV in CKD Guideline. This Executive Summary highlights key aspects of the guideline recommendations.

引用

页码：663 / 673

页数：11

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