Hallucinations in Parkinson's disease

被引：0

作者：

Moser, A ^{[1
]}

Hagenah, J ^{[1
]}

Kömpf, D ^{[1
]}

机构：

[1] Med Univ Lubeck, Neurol Klin, Klinikum Schleswig Holstein, D-23538 Lubeck, Germany

来源：

NERVENARZT | 2003年 / 74卷 / 04期

关键词：

Parkinson's disease; hallucinations; dream activity; sleep disturbances; L-dopa; dopamine agonists; serotonin antagonists;

D O I：

10.1007/s00115-003-1511-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The appearance of psychiatric symptoms is not rare in the course and treatment of Parkinson's disease. In particular, therapy with L-dopa or dopamine agonists leads to increased dream activity. As with sleep disturbances, this can be a warning signal of paranoid hallucinatory psychosis. However, isolated visual hallucinations before manifest psychosis in Parkinson's must generally be regarded as resulting from medication. They occur in up to 30% of Parkinson's patients and often involve visual and figurative hallucinations. Visual hallucinations most probably result from the combined effect on dopaminergic and serotonergic systems in the CNS. Therapy consists in normalization of H2O and electrolyte levels, control of the accompanying medication, reduction of the evening doses of anti-Parkinson's medications, and serotonin antagonists such as clozapine.

引用

页码：376 / 386

页数：21