共 50 条
- [31] BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and ratsScientific Reports, 7Martin Weber论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceTiffany Wu论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceWilliam J. Meilandt论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceSara L. Dominguez论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceHilda O. Solanoy论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceJanice A. Maloney论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceHai Ngu论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceMiriam Baca论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceChung Kung论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceLisa Lima论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceTimothy K. Earr论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceDaniel Fleck论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceShannon D. Shields论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceWilliam F. Forrest论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceOded Foreman论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceSøren Warming论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceRyan J. Watts论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of NeuroscienceKimberly Scearce-Levie论文数: 0 引用数: 0 h-index: 0机构: Genentech,Department of Neuroscience
- [32] Fueling the Alzheimer's BACE1 race with genetic insights and cyclopropyloxazine BACE1 inhibitorsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254Minatti, Ana论文数: 0 引用数: 0 h-index: 0机构: Amgen Inc, Med Chem, Thousand Oaks, CA 91320 USA Amgen Inc, Med Chem, Thousand Oaks, CA 91320 USA
- [33] BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and ratsSCIENTIFIC REPORTS, 2017, 7Weber, Martin论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAWu, Tiffany论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAMeilandt, William J.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USADominguez, Sara L.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USASolanoy, Hilda O.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAMaloney, Janice A.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USANgu, Hai论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Pathol, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USABaca, Miriam论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Pathol, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAKung, Chung论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Transgen Technol, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USALima, Lisa论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Transgen Technol, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAEarr, Timothy K.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAFleck, Daniel论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAShields, Shannon D.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAForrest, William F.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Bioinformat, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAForeman, Oded论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Pathol, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAWarming, Soren论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Mol Biol, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAWatts, Ryan J.论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USAScearce-Levie, Kimberly论文数: 0 引用数: 0 h-index: 0机构: Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA Genentech Inc, Dept Neurosci, 1 DNA Way, San Francisco, CA 94080 USA
- [34] Advancements in BACE1 and non-peptide BACE1 inhibitors for Alzheimer's diseaseINDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2018, 57 (06): : 830 - 842Shah, Nishita P.论文数: 0 引用数: 0 h-index: 0机构: Prin KM Kundnani Coll Pharm, 23 Jote Joy,RS Marg, Mumbai 400005, Maharashtra, India Prin KM Kundnani Coll Pharm, 23 Jote Joy,RS Marg, Mumbai 400005, Maharashtra, IndiaSolanki, Vivek S.论文数: 0 引用数: 0 h-index: 0机构: Prin KM Kundnani Coll Pharm, 23 Jote Joy,RS Marg, Mumbai 400005, Maharashtra, India Prin KM Kundnani Coll Pharm, 23 Jote Joy,RS Marg, Mumbai 400005, Maharashtra, IndiaGurjar, Archana S.论文数: 0 引用数: 0 h-index: 0机构: Prin KM Kundnani Coll Pharm, 23 Jote Joy,RS Marg, Mumbai 400005, Maharashtra, India Prin KM Kundnani Coll Pharm, 23 Jote Joy,RS Marg, Mumbai 400005, Maharashtra, India
- [35] BACE1 and BACE2 deficient miceNEUROBIOLOGY OF AGING, 2004, 25 : S247 - S248Dominguez, DI论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Louvain, BelgiumTournoy, JU论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Louvain, BelgiumHartmann, D论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Louvain, BelgiumReiss, K论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Louvain, BelgiumSaftig, P论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Louvain, Belgiumde Strooper, B论文数: 0 引用数: 0 h-index: 0机构: Katholieke Univ Leuven, Louvain, Belgium
- [36] Associations of CSF BACE1 with amyloid pathology, neurodegeneration, and cognition in Alzheimer's diseaseACTA NEUROPATHOLOGICA, 2024, 147 (01)Gao, Feng论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Neurodegenerat Disorder Res Ctr, Div Life Sci & Med, Hefei 230026, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaZhang, Mengguo论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaWang, Qiong论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaNi, Ming论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Dept Nucl Med, Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaLiu, Chang论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Dept Radiol, Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaDeng, Kexue论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Dept Radiol, Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaXie, Qiang论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Dept Nucl Med, Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaWang, Shicung论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Dept Nucl Med, Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaShi, Jiong论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R ChinaShen, Yong论文数: 0 引用数: 0 h-index: 0机构: Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R China Univ Sci & Technol China, Neurodegenerat Disorder Res Ctr, Div Life Sci & Med, Hefei 230026, Peoples R China Univ Sci & Technol China, Anhui Prov Key Lab Biomed Aging Res, Hefei 230001, Peoples R China Univ Sci & Technol China, Affiliated Hosp USTC 1, Inst Aging & Brain Disorders, Dept Neurol,Div Life Sci & Med, Hefei 230001, Peoples R China
- [37] Inhibition of BACE1 affected both its Aβ producing and degrading activities and increased Aβ42 and Aβ40 levels at high-level BACE1 expressionJOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (08)论文数: 引用数: h-index:机构:Leung, Rocher论文数: 0 引用数: 0 h-index: 0机构: McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, Canada McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, CanadaHerre, Fritz论文数: 0 引用数: 0 h-index: 0机构: McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, Canada McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, CanadaWalther, Lina论文数: 0 引用数: 0 h-index: 0机构: McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, Canada McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, CanadaShobo, Adeola论文数: 0 引用数: 0 h-index: 0机构: McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, Canada McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, CanadaSaftig, Paul论文数: 0 引用数: 0 h-index: 0机构: CAU Kiel, Biochem Inst, Kiel, Germany McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, CanadaHancock, Mark A.论文数: 0 引用数: 0 h-index: 0机构: McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, Canada McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, CanadaLiebsch, Filip论文数: 0 引用数: 0 h-index: 0机构: Univ Cologne, Inst Biochem, Dept Chem, Cologne, Germany McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, CanadaMulthaup, Gerhard论文数: 0 引用数: 0 h-index: 0机构: McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, Canada McGill Univ, Integrated Program Neurosci, Montreal, PQ, Canada McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ, Canada
- [38] BACE1gene variants do not influence BACE1 activity, levels of APP or Aβ isoforms in CSF in Alzheimer's diseaseMolecular Neurodegeneration, 5Annica Sjölander论文数: 0 引用数: 0 h-index: 0机构: Sahlgrenska University Hospital,Institute of Neuroscience and Physiology, Department of Neurochemistry and PsychiatryHenrik Zetterberg论文数: 0 引用数: 0 h-index: 0机构: Sahlgrenska University Hospital,Institute of Neuroscience and Physiology, Department of Neurochemistry and PsychiatryUlf Andreasson论文数: 0 引用数: 0 h-index: 0机构: Sahlgrenska University Hospital,Institute of Neuroscience and Physiology, Department of Neurochemistry and PsychiatryLennart Minthon论文数: 0 引用数: 0 h-index: 0机构: Sahlgrenska University Hospital,Institute of Neuroscience and Physiology, Department of Neurochemistry and PsychiatryKaj Blennow论文数: 0 引用数: 0 h-index: 0机构: Sahlgrenska University Hospital,Institute of Neuroscience and Physiology, Department of Neurochemistry and Psychiatry
- [39] THE DYSREGULATION OF THE AXIS BACE1/BACE1-AS IN HEART FAILUREJOURNAL OF VASCULAR RESEARCH, 2015, 52 : 35 - 36Greco, S.论文数: 0 引用数: 0 h-index: 0机构: Irccs Policlin San Donato, Milan, Italy Irccs Policlin San Donato, Milan, ItalyVoellenkle, C.论文数: 0 引用数: 0 h-index: 0机构: Irccs Policlin San Donato, Milan, Italy Irccs Policlin San Donato, Milan, ItalyZaccagnini, G.论文数: 0 引用数: 0 h-index: 0机构: Ist Sci San Raffaele, I-20132 Milan, Italy Irccs Policlin San Donato, Milan, ItalyManteiga, J.论文数: 0 引用数: 0 h-index: 0机构: Irccs Policlin San Donato, Milan, Italy Irccs Policlin San Donato, Milan, ItalyMartelli, F.论文数: 0 引用数: 0 h-index: 0机构: Irccs Policlin San Donato, Milan, Italy Irccs Policlin San Donato, Milan, Italy
- [40] CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer's diseaseALZHEIMERS RESEARCH & THERAPY, 2020, 12 (01)论文数: 引用数: h-index:机构:Dumurgier, Julien论文数: 0 引用数: 0 h-index: 0机构: Univ Paris, Inserm U1144, Paris, France Univ Paris, Paris, France Lariboisiere Fernand Widal Hosp, AP HP, Ctr Cognit Neurol, 200 Rue Faubourg St Denis, F-75010 Paris, France Univ Paris, Inserm U1144, Paris, FranceCognat, Emmanuel论文数: 0 引用数: 0 h-index: 0机构: Univ Paris, Inserm U1144, Paris, France Univ Paris, Paris, France Lariboisiere Fernand Widal Hosp, AP HP, Ctr Cognit Neurol, 200 Rue Faubourg St Denis, F-75010 Paris, France Univ Paris, Inserm U1144, Paris, FranceHourregue, Claire论文数: 0 引用数: 0 h-index: 0机构: Univ Paris, Paris, France Lariboisiere Fernand Widal Hosp, AP HP, Ctr Cognit Neurol, 200 Rue Faubourg St Denis, F-75010 Paris, France Univ Paris, Inserm U1144, Paris, FranceZetterberg, Henrik论文数: 0 引用数: 0 h-index: 0机构: Sahlgrens Univ Hosp, Clin Neurochem Lab, Molndal, Sweden Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Psychiat & Neurochem, Molndal, Sweden UK Dementia Res Inst UCL, London, England UCL Inst Neurol, Dept Neurodegenerat Dis, Queen Sq, London, England Univ Paris, Inserm U1144, Paris, FranceVanderstichele, Hugo论文数: 0 引用数: 0 h-index: 0机构: ADX Neurosci, Ghent, Belgium Univ Paris, Inserm U1144, Paris, FranceVanmechelen, Eugeen论文数: 0 引用数: 0 h-index: 0机构: ADX Neurosci, Ghent, Belgium Univ Paris, Inserm U1144, Paris, FranceBouaziz-Amar, Elodie论文数: 0 引用数: 0 h-index: 0机构: Univ Paris, Inserm U1144, Paris, France Lariboisiere Fernand Widal Hosp, AP HP, Dept Biochem, Paris, France Univ Paris, Inserm U1144, Paris, FranceBlennow, Kaj论文数: 0 引用数: 0 h-index: 0机构: Sahlgrens Univ Hosp, Clin Neurochem Lab, Molndal, Sweden Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Psychiat & Neurochem, Molndal, Sweden Univ Paris, Inserm U1144, Paris, FranceHugon, Jacques论文数: 0 引用数: 0 h-index: 0机构: Univ Paris, Inserm U1144, Paris, France Univ Paris, Paris, France Lariboisiere Fernand Widal Hosp, AP HP, Ctr Cognit Neurol, 200 Rue Faubourg St Denis, F-75010 Paris, France Univ Paris, Inserm U1144, Paris, FrancePaquet, Claire论文数: 0 引用数: 0 h-index: 0机构: Univ Paris, Inserm U1144, Paris, France Univ Paris, Paris, France Lariboisiere Fernand Widal Hosp, AP HP, Ctr Cognit Neurol, 200 Rue Faubourg St Denis, F-75010 Paris, France Univ Paris, Inserm U1144, Paris, France