Food-grade TiO2 (E171) nanoparticles cross the human placental barrier: an ex vivo study on isolated and perfused placentae

被引:0
|
作者
Guillard, A. [1 ]
Gaultier, E. [1 ]
Cartier, C. [1 ]
Devoille, L. [2 ]
Noireaux, J. [2 ]
Chevalier, L. [3 ]
Oster, C. [2 ]
Grandin, F. [1 ]
Comera, C. [1 ]
Cazanave, A. [1 ]
De Place, A. [4 ]
Morin, M. [4 ]
Vayssiere, C. [4 ]
Gambier, S. [5 ]
Feltin, N. [2 ]
De La Farge, F. [1 ]
Gayrard, V. [1 ]
Bach, V. [6 ]
Chardon, K. [6 ]
Fisicaro, P. [2 ]
Picard-Hagen, N. [1 ]
Houdeau, E. [1 ]
机构
[1] INRA ENVT, Toxalim UMR1331 Res Ctr Food Toxicol, Toulouse, France
[2] Lab Natl Metrol & Essai, Paris, France
[3] CNRS, Grp Phys Mat, UMR6634, Rouen, France
[4] Toulouse Univ Hosp, Toulouse, France
[5] Luxembourg Inst Sci & Technol, Environm Hlth Grp, Belvaux, Luxembourg
[6] Jules Verne Univ, Peritox UMR I 01 Perinatal & Tox Risk, Amiens, France
关键词
D O I
暂无
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
OP02-06
引用
收藏
页码:S64 / S64
页数:1
相关论文
共 12 条
  • [1] In vitro digestion of food grade TiO2 (E171) and TiO2 nanoparticles: physicochemical characterization and impact on the activity of digestive enzymes
    Dudefoi, William
    Rabesona, Hanitra
    Rivard, Camille
    Mercier-Bonin, Muriel
    Humbert, Bernard
    Terrisse, Helene
    Ropers, Marie-Helene
    FOOD & FUNCTION, 2021, 12 (13) : 5975 - 5988
  • [2] Toxicological impact of titanium dioxide nanoparticles and food-grade titanium dioxide (E171) on human and environmental health
    Fiordaliso, Fabio
    Bigini, Paolo
    Salmona, Mario
    Diomede, Luisa
    ENVIRONMENTAL SCIENCE-NANO, 2022, 9 (04) : 1199 - 1211
  • [3] Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion model
    A. Guillard
    E. Gaultier
    C. Cartier
    L. Devoille
    J. Noireaux
    L. Chevalier
    M. Morin
    F. Grandin
    M. Z. Lacroix
    C. Coméra
    A. Cazanave
    A. de Place
    V. Gayrard
    V. Bach
    K. Chardon
    N. Bekhti
    K. Adel-Patient
    C. Vayssière
    P. Fisicaro
    N. Feltin
    F. de la Farge
    N. Picard-Hagen
    B. Lamas
    E. Houdeau
    Particle and Fibre Toxicology, 17
  • [4] Evaluation of the cytotoxic and cellular proteome impacts of food-grade TiO2 (E171) using simulated gastrointestinal digestions and a tri-culture small intestinal epithelial model
    Cao, Xiaoqiong
    Zhang, Tong
    DeLoid, Glen M.
    Gaffrey, Matthew J.
    Weitz, Karl K.
    Thrall, Brian D.
    Qian, Wei-Jun
    Demokritou, Philip
    NANOIMPACT, 2020, 17
  • [5] Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2nanoparticles in an ex vivo placental perfusion model
    Guillard, A.
    Gaultier, E.
    Cartier, C.
    Devoille, L.
    Noireaux, J.
    Chevalier, L.
    Morin, M.
    Grandin, F.
    Lacroix, M. Z.
    Comera, C.
    Cazanave, A.
    de Place, A.
    Gayrard, V
    Bach, V
    Chardon, K.
    Bekhti, N.
    Adel-Patient, K.
    Vayssiere, C.
    Fisicaro, P.
    Feltin, N.
    de la Farge, F.
    Picard-Hagen, N.
    Lamas, B.
    Houdeau, E.
    PARTICLE AND FIBRE TOXICOLOGY, 2020, 17 (01)
  • [6] Simulated Gastric Digestion and In Vivo Intestinal Uptake of Orally Administered CuO Nanoparticles and TiO2 E171 in Male and Female Rat Pups
    Mortensen, Ninell P.
    Caffaro, Maria Moreno
    Aravamudhan, Shyam
    Beeravalli, Lakshmi
    Prattipati, Sharmista
    Snyder, Rodney W.
    Watson, Scott L.
    Patel, Purvi R.
    Weber, Frank X.
    Montgomery, Stephanie A.
    Sumner, Susan J.
    Fennell, Timothy R.
    NANOMATERIALS, 2021, 11 (06)
  • [7] Jejunal villus absorption and paracellular tight junction permeability are major routes for early intestinal uptake of food-grade TiO2 particles: an in vivo and ex vivo study in mice
    Christine Coméra
    Christel Cartier
    Eric Gaultier
    Olivier Catrice
    Quentin Panouille
    Sarah El Hamdi
    Kristof Tirez
    Inge Nelissen
    Vassilia Théodorou
    Eric Houdeau
    Particle and Fibre Toxicology, 17
  • [8] Food-related engineered nanoparticles and food-grade TiO2 impact the metabolism of a human commensal bacterial strain in physiologically relevant conditions
    Zhang, Yirong
    Huang, Wenqian
    Li, Minjie
    Li, Fangfang
    Li, Lingxiangyu
    Mortimer, Monika
    Guo, Liang-Hong
    ENVIRONMENTAL SCIENCE-NANO, 2023, 10 (01) : 251 - 268
  • [9] Toxicological impact of acute exposure to E171 food additive and TiO2 nanoparticles on a co-culture of Caco-2 and HT29-MTX intestinal cells
    Dorier, Marie
    Tisseyre, Celine
    Dussert, Fanny
    Beal, David
    Arnal, Marie-Edith
    Douki, Thierry
    Valdiglesias, Vanessa
    Laffon, Blanca
    Fraga, Sonia
    Brandao, Fatima
    Herlin-Boime, Nathalie
    Barreau, Frederick
    Rabilloud, Thierry
    Carriere, Marie
    MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2019, 845
  • [10] Jejunal villus absorption and paracellular tight junction permeability are major routes for early intestinal uptake of food-grade TiO2particles: an in vivo and ex vivo study in mice
    Comera, Christine
    Cartier, Christel
    Gaultier, Eric
    Catrice, Olivier
    Panouille, Quentin
    El Hamdi, Sarah
    Tirez, Kristof
    Nelissen, Inge
    Theodorou, Vassilia
    Houdeau, Eric
    PARTICLE AND FIBRE TOXICOLOGY, 2020, 17 (01)