Polymer Composite Optically Integrated Lab on Chip for the Detection of Ammonia

被引:17
作者
Ozhikandathil, Jayan [1 ]
Badilescu, Simona [1 ]
Packirisamy, Muthukumaran [1 ]
机构
[1] Concordia Univ, Dept Mech & Ind Engn, Opt Bio Microsyst Lab, Montreal, PQ H3G 1M8, Canada
关键词
TOTAL ANALYSIS SYSTEMS; SOLID-PHASE EXTRACTION; ALIPHATIC-AMINES; NANOCOMPOSITE; CHROMATOGRAPHY; SPECTROSCOPY; SENSOR;
D O I
10.1149/2.0121808jes
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
This paper reports a novel method to detect ammonia by using the ninhydrin - PDMS composite. The polymer composite film is prepared by integrating ninhydrin into the PDMS polymer matrix. Further, an optical lab-on-a-chip device is developed by integrating the ninhydrin-polymer composite into a microfluidic device for the detection of ammonia. The chemisorption of ammonia onto the composite resulted in the change in its optical absorption property. The proposed device has an integrated light emitting diode and photoresistor in order to measure the change in absorption and hence the detection and quantification of ammonia are performed. The response time of the sensor was found to be linear for a wide range of ammonia concentrations and it is shortest for the thin (100 mu m) composite film. The limit of detection of the proposed device is found to be as low as 2ppm. The proposed sensor platform is also demonstrated for the detection of amino acids. (C) The Author(s) 2018. Published by ECS.
引用
收藏
页码:B3078 / B3083
页数:6
相关论文
共 25 条
[1]   Gold-Poly(methyl methacrylate) Nanocomposite Films for Plasmonic Biosensing Applications [J].
Alsawafta, Mohammed ;
Badilescu, Simona ;
Paneri, Abhilash ;
Vo-Van Truong ;
Packirisamy, Muthukumaram .
POLYMERS, 2011, 3 (04) :1833-1848
[2]   Microfluidic devices for cellomics: a review [J].
Andersson, H ;
van den Berg, A .
SENSORS AND ACTUATORS B-CHEMICAL, 2003, 92 (03) :315-325
[3]   COULOMETRIC TITRATION OF AMMONIA WITH HYPOBROMITE [J].
ARCAND, GM ;
SWIFT, EH .
ANALYTICAL CHEMISTRY, 1956, 28 (04) :440-443
[4]   Micro total analysis systems. 2. Analytical standard operations and applications [J].
Auroux, PA ;
Iossifidis, D ;
Reyes, DR ;
Manz, A .
ANALYTICAL CHEMISTRY, 2002, 74 (12) :2637-2652
[5]   Development of an automated method for simultaneous determination of low molecular weight aliphatic amines and ammonia in ambient air by diffusion scrubber coupled to ion chromatography [J].
Chang, IH ;
Lee, CG ;
Lee, DS .
ANALYTICAL CHEMISTRY, 2003, 75 (22) :6141-6146
[6]   Optical rubbery ormosils sensor for the detection of ammonia [J].
Chen, X ;
Dai, YJ ;
Li, Z ;
Zhang, ZX ;
Wang, XR .
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 2001, 370 (08) :1048-1051
[7]   Studies on tin oxide-intercalated polyaniline nanocomposite for ammonia gas sensing applications [J].
Deshpande, N. G. ;
Gudage, Y. G. ;
Sharma, Ramphal ;
Vyas, J. C. ;
Kim, J. B. ;
Lee, Y. P. .
SENSORS AND ACTUATORS B-CHEMICAL, 2009, 138 (01) :76-84
[8]   Synthesis and Surface Modification of Poly (dimethylsiloxane) - Gold Nanocomposite Films for Biosensing Applications [J].
Devi, Pooja ;
Mahmoud, Alaa Yahya ;
Badilescu, Simona ;
Packirisamy, Muthukumaran ;
Jeevanandam, Pethaiyan ;
Vo-Van Truong .
PROCEEDINGS OF THE FIRST INTERNATIONAL CONFERENCE ON BIOSCIENCES, (BIOSCIENCESWORLD 2010), 2010, :1-5
[9]  
Khosla A., 2013, U.S. Patent, Patent No. [No. 8,357,858, 8357858]
[10]   SPECTROPHOTOMETRIC DETERMINATION OF AMMONIA - A STUDY OF A MODIFIED BERTHELOT REACTION USING SALICYLATE AND DICHLOROISOCYANURATE [J].
KROM, MD .
ANALYST, 1980, 105 (1249) :305-316