Polymer Composite Optically Integrated Lab on Chip for the Detection of Ammonia

被引:16
|
作者
Ozhikandathil, Jayan [1 ]
Badilescu, Simona [1 ]
Packirisamy, Muthukumaran [1 ]
机构
[1] Concordia Univ, Dept Mech & Ind Engn, Opt Bio Microsyst Lab, Montreal, PQ H3G 1M8, Canada
关键词
TOTAL ANALYSIS SYSTEMS; SOLID-PHASE EXTRACTION; ALIPHATIC-AMINES; NANOCOMPOSITE; CHROMATOGRAPHY; SPECTROSCOPY; SENSOR;
D O I
10.1149/2.0121808jes
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
This paper reports a novel method to detect ammonia by using the ninhydrin - PDMS composite. The polymer composite film is prepared by integrating ninhydrin into the PDMS polymer matrix. Further, an optical lab-on-a-chip device is developed by integrating the ninhydrin-polymer composite into a microfluidic device for the detection of ammonia. The chemisorption of ammonia onto the composite resulted in the change in its optical absorption property. The proposed device has an integrated light emitting diode and photoresistor in order to measure the change in absorption and hence the detection and quantification of ammonia are performed. The response time of the sensor was found to be linear for a wide range of ammonia concentrations and it is shortest for the thin (100 mu m) composite film. The limit of detection of the proposed device is found to be as low as 2ppm. The proposed sensor platform is also demonstrated for the detection of amino acids. (C) The Author(s) 2018. Published by ECS.
引用
收藏
页码:B3078 / B3083
页数:6
相关论文
共 50 条
  • [1] Integrated Lasers for Polymer Lab-on-a-Chip Systems
    Mappes, Timo
    Vannahme, Christoph
    Grossmann, Tobias
    Beck, Torsten
    Wienhold, Tobias
    Bog, Uwe
    Breithaupt, Felix
    Brammer, Marko
    Liu, Xin
    Klinkhammer, Sonke
    Laue, Thomas
    Hirtz, Michael
    Christiansen, Mads Brokner
    Kristensen, Anders
    Lemmer, Uli
    Kalt, Heinz
    2012 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO), 2012,
  • [2] Highly integrated lab-on-a-chip for fluorescence detection
    Guduru, Surya S. K.
    Scotognella, Francesco
    Chiasera, Alessandro
    Sreeramulu, Valligatla
    Criante, Luigino
    Vishnubhatia, Krishna Chaitanya
    Ferrari, Maurizio
    Ramponi, Roberta
    Lanzani, Guglielmo
    Vazquez, Rebeca Martinez
    OPTICAL ENGINEERING, 2016, 55 (09)
  • [3] Lab-on-chip detection of biomolecules with integrated sensors
    Conde, J.
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2013, 42 : S108 - S108
  • [4] Integrated electrochemical detection for lab on a chip analytical microsystems
    Pai, RS
    Roussel, TJ
    Crain, MM
    Jackson, DJ
    Conklin, JA
    Baldwin, RP
    Keynton, RS
    Naber, JF
    Walsh, KM
    FOURTEENTH BIENNIAL UNIVERSITY/GOVERNMENT/INDUSTRY MICROELECTRONICS SYMPOSIUM, PROCEEDINGS, 2001, : 167 - 170
  • [5] Polymer Lab-on-a-Chip system with electrical detection
    Muehlberger, Holger
    Hwang, Wonhee
    Guber, Andreas E.
    Saile, Volker
    Hoffmann, Werner
    IEEE SENSORS JOURNAL, 2008, 8 (5-6) : 572 - 579
  • [6] Optically Driven Mobile Integrated Micro-Tools for a Lab-on-a-Chip
    Liu, Yi-Jui
    Lee, Yi-Hsiung
    Lin, Yu-Sheng
    Tsou, Chingfu
    Baldeck, Patrice L.
    Lin, Chih-Lang
    ACTUATORS, 2013, 2 (02): : 19 - 26
  • [7] Optical particle detection integrated in a dielectrophoretic lab-on-a-chip
    Cui, L
    Zhang, T
    Morgan, H
    JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2002, 12 (01) : 7 - 12
  • [8] Integrated Lab on Chip for Detection of Cells and Micro-organisms
    Salm, Eric
    Duarte, Carlos
    Bashir, Rashid
    2012 IEEE PHOTONICS CONFERENCE (IPC), 2012, : 145 - +
  • [9] An integrated fluorescence detection system for lab-on-a-chip applications
    Novak, Lukas
    Neuzil, Pavel
    Pipper, Juergen
    Zhang, Yi
    Lee, Shinhan
    LAB ON A CHIP, 2007, 7 (01) : 27 - 29
  • [10] Lab-on-a-chip detects ammonia
    van den Berg, A
    TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2004, 23 (06) : VII - VIII