Circulating tumor cells: Cornerstone of personalized medicine

被引:2
作者
Rafii, A. [1 ,2 ]
Vidal, F. [1 ]
Rathat, G. [2 ]
Alix-Panabieres, C. [3 ,4 ]
机构
[1] Weill Cornell Med Coll, Dept Genet Med & Obstet & Gynecol, Lab Cellules Souches & Microenvironm, New York, NY 10020 USA
[2] Univ Montpellier I, CHRU, Hop Arnaud de Villeneuve, Dept Chirurg Gynecol, F-34093 Montpellier, France
[3] Univ Montpellier I, CHRU,Lab Cellules Circulantes Rares Humaines, Hop St Eloi,Inst Med Regeneratrice & Biotherapie, Dept Biopathol Cellulaire & Tissulaire Tumeurs, Montpellier, France
[4] Inst Univ Rech Clin, Epidemiol EA2415, F-34093 Montpellier, France
来源
JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION | 2014年 / 43卷 / 09期
关键词
Circulating tumor cells; Personalized medicine; Liquid biopsy; METASTATIC BREAST-CANCER; PROGRESSION-FREE SURVIVAL; BONE-MARROW; PERIPHERAL-BLOOD; PROSTATE-CANCER; LIQUID BIOPSY; HER2; STATUS; EXPRESSION; CARCINOMA; THERAPY;
D O I
10.1016/j.jgyn.2014.06.009
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Cancer treatment has evolved toward personalized medicine. It is mandatory for clinicians to ascertain tumor biological features in order to optimize patients' treatment. Identification and characterization of circulating tumor cells demonstrated a prognostic value in many solid tumors. Here, we describe the main technologies for identification and characterization of circulating tumor cells and their clinical application in gynecologic and breast cancers. (C) 2014 Published by Elsevier Masson SAS.
引用
收藏
页码:640 / 648
页数:9
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