Cobalt interference in iron-uptake could inhibit growth in Pseudomonas aeruginosa

被引：8
|
作者：
Kothamasi, D [1 ]
Kothamasi, S [1 ]
机构：
[1] Univ Delhi, Sch Environm Studies, Ctr Environm Management Degraded Ecosyst, Delhi 110007, India
来源：
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY | 2004年 / 20卷 / 07期
关键词：
citrate; cobalt; iron-uptake; Pseudomonas aeruginosa;
D O I：
10.1007/s11274-004-5810-4
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The present study was undertaken to investigate the possible inhibition of growth in Pseudomonas aeruginosa by interfering with its iron-uptake mechanism. Cobalt was employed as a possible competitive inhibitor of iron-uptake because of its similar size. The results indicate that cobalt competes effectively with iron for uptake by the bacterial cells and interference with iron-uptake could provide an effective means for inhibiting growth in P. aeruginosa.
引用
收藏
页码：755 / 758
页数：4
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