A fetus with Prader-Willi syndrome showing normal diurnal rhythm and abnormal ultradian rhythm on heart rate monitoring

被引：15

作者：

Hiroi, H ^{[1
]}

Kozuma, S ^{[1
]}

Hayashi, N ^{[1
]}

Unno, N ^{[1
]}

Fujii, T ^{[1
]}

Tsutsumi, O ^{[1
]}

Okai, T ^{[1
]}

Taketani, Y ^{[1
]}

机构：

[1] Univ Tokyo, Dept Obstet & Gynecol, Bunkyo Ku, Tokyo 113, Japan

来源：

FETAL DIAGNOSIS AND THERAPY | 2000年 / 15卷 / 05期

关键词：

Prader-Willi syndrome; rhythm; fetus; heart rate;

D O I：

10.1159/000021026

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Clinical features of Prader-Willi syndrome in neonates are marked hypotonia with the absence of crying and feeding difficulty so that prenatal diagnosis of Prader-Willi syndrome is strongly hoped in order to provide appropriate medical and psychological care for neonates and their families. However, the clinical picture of Prader-Willi syndrome in utero has not been well described. We report a pregnancy associated with Prader-Willi syndrome manifesting polyhydramnios, large biparietal diameter of the fetus and characteristic feta I heart rate pattern: prolonged inactive periods and diurnal variation of the incidence of heart rate accelerations, These findings may offer a clue to the prenatal diagnosis of Prader-Willi syndrome, although molecular cytogenetics is mandatory for the definite diagnosis. Copyright (C) 2000 S. Karger AG, Basel.

引用

页码：304 / 307

页数：4