Prenatal exposure to binge drinking and cognitive and behavioral outcomes at age 7 years

被引:86
作者
Bailey, BN
Delaney-Black, V
Covington, CY
Ager, J
Janisse, J
Hannigan, JH
Sokol, RJ
机构
[1] E Tennessee State Univ, James H Quillen Coll Med, Dept Family Med, Johnson City, TN 37614 USA
[2] Wayne State Univ, Dept Pediat, Detroit, MI USA
[3] Wayne State Univ, Ctr Hlth Care Effectiveness Res, Detroit, MI USA
[4] Wayne State Univ, Sch Med, Dept Obstet & Gynecol, Detroit, MI 48201 USA
[5] Wayne State Univ, Dept Psychol, Detroit, MI 48202 USA
[6] Univ Calif Los Angeles, Sch Nursing, Los Angeles, CA 90024 USA
关键词
prenatal alcohol exposure; binge drinking; child outcome;
D O I
10.1016/j.ajog.2004.05.048
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: The goal of this study was to examine differential effects of amount and pattern of prenatal alcohol exposure on child outcome. Study design: Alcohol use was assessed at each prenatal visit, and IQ and behavior were measured at age 7 years. Results: After control for confounders, the amount of exposure was unrelated to IQ score and behavior for >500 black 7-year-old children. However, children who were exposed to binge drinking were 1.7 times more likely to have IQ scores in the mentally retarded range and 2.5 times more likely to have clinically significant levels of delinquent behavior. Conclusion: During prenatal care, clinicians should attend not only to amount but also to the pattern of alcohol intake, because of the elevated risk for cognitive deficits and long-term behavioral abnormality. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:1037 / 1043
页数:7
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