Dihydroxylation of 2-vinylaziridine:: efficient synthesis of D-ribo-phytosphingosine

被引：49
作者：
Yoon, Hyo Jae
Kim, Yong-Woo
Lee, Baeck Kyoung
Lee, Won Koo
Kim, Yongeun
Ha, Hyun-Joon [1 ]
机构：
[1] Sogang Univ, Dept Chem, Seoul 121742, South Korea
[2] Sogang Univ, Program Integrated Biotechnol, Seoul 121742, South Korea
[3] Hankuk Univ Foreign Studies, Dept Chem, Yongin 449791, South Korea
来源：
CHEMICAL COMMUNICATIONS | 2007年 / 01期
关键词：
D O I：
10.1039/b612740a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient and highly stereoselective synthesis of D-ribo-(2S, 3S, 4R)-phytosphingosine was accomplished in 62% overall yield starting from commercially available (2S)-hydroxymethylaziridine via osmium-catalyzed asymmetric dihydroxylation as a key step.
引用
收藏
页码：79 / 81
页数：3
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