Visible light-promoted metal-free sp3-C-H fluorination

被引：118

作者：

Xia, Ji-Bao ^{[1
]}

Zhu, Chen ^{[1
]}

Chen, Chuo ^{[1
]}

机构：

[1] Univ Texas SW Med Ctr Dallas, Dept Biochem, Dallas, TX 75390 USA

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 79期

关键词：

C-H FLUORINATION; BONDS; MONOFLUORINATION; PHOTOCATALYSIS; ACTIVATION; CATALYSIS;

D O I：

10.1039/c4cc05650g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Photoexcited acetophenone can catalyze the fluorination of unactivated C(sp(3))-H groups. While acetophenone, a colorless oil, only has a trace amount of absorption in the visible light region, its photoexcitation can be achieved by irradiation with light generated by a household compact fluorescent lamp (CFL). This operational simple method provides improved substrate scope for the direct incorporation of a fluorine atom into simple organic molecules. CFL-irradiation can also be used to promote certain classic UV-promoted photoreactions of colorless monoarylketones and enones/enals.

引用

页码：11701 / 11704

页数：4

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