Visible light-promoted metal-free sp3-C-H fluorination

被引：114
作者：
Xia, Ji-Bao [1 ]
Zhu, Chen [1 ]
Chen, Chuo [1 ]
机构：
[1] Univ Texas SW Med Ctr Dallas, Dept Biochem, Dallas, TX 75390 USA
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 79期
关键词：
C-H FLUORINATION; BONDS; MONOFLUORINATION; PHOTOCATALYSIS; ACTIVATION; CATALYSIS;
D O I：
10.1039/c4cc05650g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Photoexcited acetophenone can catalyze the fluorination of unactivated C(sp(3))-H groups. While acetophenone, a colorless oil, only has a trace amount of absorption in the visible light region, its photoexcitation can be achieved by irradiation with light generated by a household compact fluorescent lamp (CFL). This operational simple method provides improved substrate scope for the direct incorporation of a fluorine atom into simple organic molecules. CFL-irradiation can also be used to promote certain classic UV-promoted photoreactions of colorless monoarylketones and enones/enals.
引用
收藏
页码：11701 / 11704
页数：4
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