Therapeutic treasures from the deep

被引：33
作者：
Hopwood, David A. [1 ]
机构：
[1] John Innes Ctr Plant Sci Res, Dept Mol Microbiol, Norwich NR4 7UH, Norfolk, England
来源：
NATURE CHEMICAL BIOLOGY | 2007年 / 3卷 / 08期
关键词：
D O I：
10.1038/nchembio0807-457
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Sequencing of the genome of a newly isolated marine actinomycete has revealed the potential to make a gamut of interesting compounds with potential as therapeutic agents. Deep-sea environments may yield new chemical structures not found in microbes from traditional terrestrial habitats.
引用
收藏
页码：457 / 458
页数：3
相关论文
共 8 条
  • [1] Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
    Bentley, SD
    Chater, KF
    Cerdeño-Tárraga, AM
    Challis, GL
    Thomson, NR
    James, KD
    Harris, DE
    Quail, MA
    Kieser, H
    Harper, D
    Bateman, A
    Brown, S
    Chandra, G
    Chen, CW
    Collins, M
    Cronin, A
    Fraser, A
    Goble, A
    Hidalgo, J
    Hornsby, T
    Howarth, S
    Huang, CH
    Kieser, T
    Larke, L
    Murphy, L
    Oliver, K
    O'Neil, S
    Rabbinowitsch, E
    Rajandream, MA
    Rutherford, K
    Rutter, S
    Seeger, K
    Saunders, D
    Sharp, S
    Squares, R
    Squares, S
    Taylor, K
    Warren, T
    Wietzorrek, A
    Woodward, J
    Barrell, BG
    Parkhill, J
    Hopwood, DA
    [J]. NATURE, 2002, 417 (6885) : 141 - 147
  • [2] Regulation of secondary metabolism in streptomycetes
    Bibb, MJ
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2005, 8 (02) : 208 - 215
  • [3] Developing a new resource for drug discovery: marine actinomycete bacteria
    Fenical, William
    Jensen, Paul R.
    [J]. NATURE CHEMICAL BIOLOGY, 2006, 2 (12) : 666 - 673
  • [4] Haynes SW, 2007, CURR OPIN DRUG DISC, V10, P203
  • [5] Hopwood DA, 2007, STREPTOMYCES NATURE
  • [6] Soil to genomics:: The Streptomyces chromosome
    Hopwood, David A.
    [J]. ANNUAL REVIEW OF GENETICS, 2006, 40 : 1 - 23
  • [7] Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
    Ikeda, H
    Ishikawa, J
    Hanamoto, A
    Shinose, M
    Kikuchi, H
    Shiba, T
    Sakaki, Y
    Hattori, M
    Omura, S
    [J]. NATURE BIOTECHNOLOGY, 2003, 21 (05) : 526 - 531
  • [8] Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica
    Udwary, Daniel W.
    Zeigler, Lisa
    Asolkar, Ratnakar N.
    Singan, Vasanth
    Lapidus, Alla
    Fenical, William
    Jensen, Paul R.
    Moore, Bradley S.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (25) : 10376 - 10381
1