Design strategies for lab-on-a-molecule probes and orthogonal sensing

被引:142
作者
Chen, Kun [1 ]
Shu, Qinghai [2 ]
Schmittel, Michael [1 ]
机构
[1] Univ Siegen, Ctr Micro & Nanochem & Engn, D-57068 Siegen, Germany
[2] Beijing Inst Technol, Sch Mat Sci & Engn, Beijing 100081, Peoples R China
关键词
SELECTIVE FLUORESCENT SENSOR; INTRAMOLECULAR CHARGE-TRANSFER; QUANTITATIVE MULTIION ANALYSIS; DIFFERENT EMISSION CHANNELS; AQUEOUS-SOLUTION; LOGIC GATE; OFF-ON; SINGLE-MOLECULE; LIVING CELLS; COLORIMETRIC RECOGNITION;
D O I
10.1039/c4cs00263f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This review highlights the currently exploited working concepts of lab-on-a-molecule probes, with a particular focus on what is required for multianalyte detection and quantification in competitive assays. Both, chemosensor and chemodosimeter approaches are considered. The multifaceted design strategies and the orthogonal protocols are evaluated in order to identify and categorise the successful conceptions and to single out unknown territory and challenges for future work.
引用
收藏
页码:136 / 160
页数:25
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