Lymph Node Involvement and the Clinical Stage as Predictors of the Survival of Patients With Adenoid Cystic Carcinoma of the Head and Neck: A Systematic Review and Meta-Analysis

被引：3
作者：
Alsarraj, Mazin [1 ]
Alshehri, Sami M. [2 ]
Qattan, Abdulrahman [2 ]
Mofti, Abdelelah [3 ]
Wazqer, Lana [2 ]
Bukhari, Sumayiah [2 ]
Shamsaldin, Aisha [2 ]
Rajab, Rahaf [2 ]
机构：
[1] King Fahad Gen Hosp, Otolaryngol Head & Neck Surg, Jeddah, Saudi Arabia
[2] King Abdullah Med Complex, Otolaryngol Head & Neck Surg, Jeddah, Saudi Arabia
[3] Univ Jeddah, Otolaryngol Head & Neck Surg, Jeddah, Saudi Arabia
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 10期
关键词：
stage; salivary gland tumor; head and neck tumors; lymph node status; adenoid cystic carcinoma (acc); PARA-NASAL SINUSES; SALIVARY-GLAND TUMORS; VASCULAR INVASION; RECURRENCE; EXPRESSION;
D O I：
10.7759/cureus.30780
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In the treatment of various patients, the presence of lymphovascular invasion is a prognostic determinant, often taken into account by surgeons and oncologists. The exact frequency and prognostic impacts of this microscopic event in adenoid cystic carcinoma (ACC) patients are, however, not clear. This systematic review and meta-analysis aimed to investigate the lymph node involvement and the clinical stage of cancer as predictors of ACC prognosis. A systematic search was conducted covering a number of databases, including PubMed, Science Direct, Google Scholar, Web of Science, and EBSCO. A total of three studies were included in this analysis, with 591 participants, 247 of whom were males. Lymph node involvement and clinical stage were demonstrated as significant bad prognosis factors among ACC patients (HR = 1.48, 95% CI, 1.00, 1.96; P<0.0001). We found that lymph node involvement and clinical stage of the cancer are both significant predictors of bad prognosis of ACC.
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页数：6
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