Environmentally relevant concentrations of benzo[a]pyrene affect steroid levels and affect gonad of male scallop Chlamys farreri

被引：10
|
作者：
Tian, Shuangmei [1 ]
Pan, Luqing [1 ]
Tao, Yanxia [1 ]
Sun, Xiaohua [1 ]
机构：
[1] Ocean Univ China, Minist Educ, Coll Fisheries, Key Lab Mariculture, Qingdao 266003, Peoples R China
来源：
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 2015年 / 114卷
基金：
高等学校博士学科点专项科研基金; 中国国家自然科学基金;
关键词：
Benzo[a]pyrene; Chlamys farreri; Steroids levels; Tissue lesion; Reproductive toxicity; POLYCYCLIC AROMATIC-HYDROCARBONS; REPRODUCTIVE-CYCLE; MYTILUS-EDULIS; MYA-ARENARIA; CRASSOSTREA-GIGAS; DIGESTIVE GLAND; SEX STEROIDS; EXPOSURE; MUSSEL; ESTRADIOL-17-BETA;
D O I：
10.1016/j.ecoenv.2015.01.019
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Sexually mature male Chlamys farreri were exposed to benzotalpyrene for 10 days at four concentrations at 0, 0.025, 0.5 and 10 mu g/L. Fluctuations in sex steroids during the exposure period were observed, which indicated that sex steroids have a role in gamete development. Exposure to B[a]P altered levels of 17 beta-estradiol, testosterone, and progesterone. Furthermore, B[a]P treatments induced oxidative stress in a dose-dependent manner on spermary of scallop and led to delayed development and damaged spermatid in germinal epithelium of spermary. Overall, B[a]P affected the steroid levels and induced gonadal toxicity at environmentally relevant concentrations. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码：150 / 156
页数：7
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