A colorimetric and fluorometric dual-modal assay for mercury ion by a molecule

被引:263
作者
Yuan, Mingjian [1 ]
Li, Yuliang
Li, Junbo
Li, Cuihong
Liu, Xiaofeng
Lv, Jing
Xu, Jialiang
Liu, Huibiao
Wang, Shu
Zhu, Daoben
机构
[1] Chinese Acad Sci, CAS Key Lab Organ Solids, Inst Chem, BNLMS, Beijing 100080, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China
关键词
D O I
10.1021/ol0706399
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis and sensing characteristics of a new class of colorimetric and fluorometric dual-modal probe for mercury ion are outlined. Judicious placement of two dithia-dioxa-aza macrocycles on the BODIPY chromophore generates this interesting molecule. A highly Hg2+-selective fluorescence enhancing property (> 7-fold) in conjunction with a visible colorimetric change from purple to red-pink can be observed, leading to potential fabrication of both "naked-eye" and ratiometric fluorescent detection of Hg2+.
引用
收藏
页码:2313 / 2316
页数:4
相关论文
共 30 条
[1]   A highly potassium-selective ratiometric fluorescent indicator based on BODIPY azacrown ether excitable with visible light [J].
Baruah, M ;
Qin, WW ;
Vallée, RAL ;
Beljonne, D ;
Rohand, T ;
Dehaen, W ;
Boens, N .
ORGANIC LETTERS, 2005, 7 (20) :4377-4380
[2]   ABSOLUTE QUANTUM YIELD DETERMINATION BY THERMAL BLOOMING - FLUORESCEIN [J].
BRANNON, JH ;
MAGDE, D .
JOURNAL OF PHYSICAL CHEMISTRY, 1978, 82 (06) :705-709
[3]   Ion sensing coupled to resonance energy transfer: A highly selective and sensitive ratiometric fluorescent chemosensor for Ag(I) by a modular approach [J].
Coskun, A ;
Akkaya, EU .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (30) :10464-10465
[4]   Signal ratio amplification via modulation of resonance energy transfer: Proof of principle in an emission ratiometric Hg(II) sensor [J].
Coskun, Ali ;
Akkaya, Engin U. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (45) :14474-14475
[5]  
CZARNIK AW, 1992, FLUORESCENT CHEMOSEN
[6]   Combining luminescence, coordination and electron transfer for signalling purposes [J].
de Silva, AP ;
Fox, DB ;
Huxley, AJM ;
Moody, TS .
COORDINATION CHEMISTRY REVIEWS, 2000, 205 :41-57
[7]   Signaling recognition events with fluorescent sensors and switches [J].
de Silva, AP ;
Gunaratne, HQN ;
Gunnlaugsson, T ;
Huxley, AJM ;
McCoy, CP ;
Rademacher, JT ;
Rice, TE .
CHEMICAL REVIEWS, 1997, 97 (05) :1515-1566
[8]   Coupling selectivity with sensitivity in an integrated chemosensor framework:: Design of a Hg2+-responsive probe, operating above 500 nm [J].
Descalzo, AB ;
Martínez-Máñez, R ;
Radeglia, R ;
Rurack, K ;
Soto, J .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (12) :3418-3419
[9]   Highly sensitive fluorescence probes for nitric oxide based on boron dipyrromethene chromophore-rational design of potentially useful bioimaging fluorescence probe [J].
Gabe, Y ;
Urano, Y ;
Kikuchi, K ;
Kojima, H ;
Nagano, T .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (10) :3357-3367
[10]   Cognitive performance of children prenatally exposed to "safe" levels of methylmercury [J].
Grandjean, P ;
Weihe, P ;
White, RF ;
Debes, F .
ENVIRONMENTAL RESEARCH, 1998, 77 (02) :165-172