The effect of estrogen on tendon and ligament metabolism and function

被引:67
作者
Leblanc, D. R. [1 ]
Schneider, M. [2 ]
Angele, P. [2 ]
Vollmer, G. [3 ]
Docheva, D. [2 ,4 ]
机构
[1] Ludwig Maximilian Univ Munich, Expt Surg & Regenerat Med, Dept Surg, Munich, Germany
[2] Univ Regensburg, Dept Trauma Surg, Med Ctr, Expt Trauma Surg, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany
[3] Tech Univ Dresden, Inst Zool, Mol Cell Physiol & Endocrinol, Dresden, Germany
[4] Med Univ Plovdiv, Dept Med Biol, Plovdiv, Bulgaria
关键词
Estrogen; Musculoskeletal tissues; Tendons and ligaments; Tendon cells; ANTERIOR CRUCIATE LIGAMENT; HORMONE REPLACEMENT THERAPY; RELAXIN RECEPTOR ISOFORMS; MESENCHYMAL STEM-CELLS; COLLAGEN CROSS-LINKING; CARPAL-TUNNEL SYNDROME; SKELETAL-MUSCLE; ACHILLES-TENDON; MECHANICAL-PROPERTIES; MENSTRUAL-CYCLE;
D O I
10.1016/j.jsbmb.2017.06.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tendons and ligaments are crucial structures inside the musculoskeletal system. Still many issues in the treatment of tendon diseases and injuries have yet not been resolved sufficiently. In particular, the role of estrogen like compound (ELC) in tendon biology has received until now little attention in modern research, despite ELC being a well-studied and important factor in the physiology of other parts of the musculoskeletal system. In this review we attempt to summarize the available information on this topic and to determine many open questions in this field.
引用
收藏
页码:106 / 116
页数:11
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