In vitro study of the mesenchymal stem cells-conditional media role in skin wound healing process: A systematic review

被引:8
|
作者
Heydari, Mohammad Bagher [1 ]
Ghanbari-Movahed, Zahra [2 ]
Heydari, Maryam [3 ]
Farzaei, Mohammad Hosein [4 ]
机构
[1] Kermanshah Univ Med Sci KUMS, Taleghani Hosp, Kermanshah, Iran
[2] Kermanshah Univ Med Sci, Med Biol Res Ctr, Kermanshah, Iran
[3] Zabol Univ Med Sci, Dept Pharm, Zabol, Iran
[4] Kermanshah Univ Med Sci, Med Technol Res Ctr, Hlth Technol Inst, Kermanshah 6734667149, Iran
关键词
conditional media; mesenchymal stem cells; skin; wound healing; STROMAL CELLS; REGENERATIVE MEDICINE; INFLAMMATORY CELLS; SECRETORY FACTORS; GROWTH-FACTORS; REPAIR; PROLIFERATION; MIGRATION; KERATINOCYTES; MECHANISMS;
D O I
10.1111/iwj.13796
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Mesenchymal stromal cell (MSC)-conditioned medium (CM) offers a potential opportunity in the skin wound healing treatment. In this systematic review, an overview of the knowledge on this topic has been provided. A multistep search of the PubMed, Scopus and Science Direct database has been performed to identify papers on MSCs-conditional media used in skin wound healing. Eligibility checks were performed based upon predefined selection criteria. Of the 485 articles initially identified, consequently, only 96 articles apparently related to MSC-conditional media were initially assessed for eligibility. Finally, the 32 articles, strictly regarding the in vitro use of MSCs-conditional media in skin wounds, were analysed. The information analysed highlights the efficacy of MSCs-conditional media on skin wound healing in vitro models. The outcome of this review may be used to guide pre-clinical and clinical studies on the role of MSCs-conditional media in skin wound healing.
引用
收藏
页码:2210 / 2223
页数:14
相关论文
共 50 条
  • [21] Epigallocatechin-3-gallate augments therapeutic effects of mesenchymal stem cells in skin wound healing
    Li, Min
    Xu, Jingxing
    Shi, Tongxin
    Yu, Haiyang
    Bi, Jianping
    Chen, Guanzhi
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2016, 43 (11): : 1115 - 1124
  • [22] Wound Healing Effect of Conditioned Media Obtained From Adipose Tissue on Human Skin Cells A Comparative in Vitro Study
    Kober, Johanna
    Gugerell, Alfred
    Schmid, Melanie
    Zeyda, Maximilian
    Buchberger, Elisabeth
    Nickl, Stefanie
    Hacker, Stefan
    Ankersmit, Hendrik Jan
    Keck, Maike
    ANNALS OF PLASTIC SURGERY, 2016, 77 (02) : 156 - 163
  • [23] Adipose-derived stem cells in wound healing of full-thickness skin defects: a review of the literature
    Huayllani, Maria T.
    Sarabia-Estrada, Rachel
    Restrepo, David J.
    Boczar, Daniel
    Sisti, Andrea
    Nguyen, Justin H.
    Rinker, Brian D.
    Moran, Steven L.
    Quinones-Hinojosa, Alfredo
    Forte, Antonio J.
    JOURNAL OF PLASTIC SURGERY AND HAND SURGERY, 2020, 54 (05) : 263 - 279
  • [24] Effect of Pig-Adipose-Derived Stem Cells' Conditioned Media on Skin Wound-Healing Characteristics In Vitro
    Wisniewska, Joanna
    Slyszewska, Magda
    Stalanowska, Karolina
    Walendzik, Katarzyna
    Kopcewicz, Marta
    Machcinska, Sylwia
    Gawronska-Kozak, Barbara
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (11)
  • [25] Comparison of Effects Exosomes Derived from Mesenchymal Stem Cells and Other Cells on Wound Healing: A Systematic Review
    Momeni, Mahdyar
    Ahmadpour, Fathollah
    TRAUMA MONTHLY, 2024, 29 (04) : 1180 - 1187
  • [26] Extracellular Vesicles Derived from Mesenchymal Stem Cells Promote Wound Healing and Skin Regeneration by Modulating Multiple Cellular Changes: A Brief Review
    Zhang, Weiyuan
    Ling, Yang
    Sun, Yang
    Xiao, Fengjun
    Wang, Lisheng
    GENES, 2023, 14 (08)
  • [27] Microvesicles enhance the mobility of human diabetic adipose tissue-derived mesenchymal stem cells in vitro and improve wound healing in vivo
    Nhu Thuy Trinh
    Yamashita, Toshiharu
    Tran Cam Tu
    Kato, Toshiki
    Ohneda, Kinuko
    Sato, Fujio
    Ohneda, Osamu
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 473 (04) : 1111 - 1118
  • [28] Concise Review: Clinical Translation of Wound Healing Therapies Based on Mesenchymal Stem Cells
    Jackson, Wesley M.
    Nesti, Leon J.
    Tuan, Rocky S.
    STEM CELLS TRANSLATIONAL MEDICINE, 2012, 1 (01) : 44 - 50
  • [29] Role of whole bone marrow, whole bone marrow cultured cells, and mesenchymal stem cells in chronic wound healing
    Rodriguez-Menocal, Luis
    Shareef, Shahjahan
    Salgado, Marcela
    Shabbir, Arsalan
    Van Badiavas, Evangelos
    Stem Cell Research & Therapy, 2015, 6
  • [30] The role of placenta-derived mesenchymal stem cells in healing of induced full-thickness skin wound in a mouse model
    Abd-Allah, Somia H.
    El-Shal, Amal S.
    Shalaby, Sally M.
    Abd-Elbary, Eman
    Mazen, Nehad F.
    Abdel Kader, Rania R.
    IUBMB LIFE, 2015, 67 (09) : 701 - 709