Targeted, triggered drug delivery to tumor and biofilm microenvironments

被引:89
作者
Benoit, Danielle S. W. [1 ,2 ,3 ]
Koo, Hyun [4 ,5 ,6 ,7 ]
机构
[1] Univ Rochester, Dept Biomed Engn, Rochester, NY USA
[2] Univ Rochester, Dept Chem Engn, Rochester, NY 14627 USA
[3] Univ Rochester, Med Ctr, Ctr Musculoskeletal Res, Rochester, NY 14642 USA
[4] Univ Penn, Biofilm Res Lab, Levy Ctr Oral Hlth, Sch Dent Med, Philadelphia, PA 19104 USA
[5] Univ Penn, Sch Dent Med, Dept Orthodont, Philadelphia, PA 19104 USA
[6] Univ Penn, Sch Dent Med, Div Pediat Dent, Philadelphia, PA 19104 USA
[7] Univ Penn, Sch Dent Med, Div Community Oral Hlth, Philadelphia, PA 19104 USA
关键词
biofilm; extracellular matrix; microenvironment; nanomedicine; nanoparticles; tumor; ENHANCED PERMEABILITY; BACTERIAL BIOFILMS; PH; NANOPARTICLES; MATRIX; NANOCARRIERS; ANTIBIOTICS; INFECTION; VIRULENCE; SYSTEMS;
D O I
10.2217/nnm-2016-0014
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:873 / 879
页数:7
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