Antiretroviral therapy in HIV-infected children

被引：0

作者：

Fan, Conghai ^{[1
]}

Zhang, Fengchao ^{[1
]}

Chen, Chao ^{[1
]}

机构：

[1] Xuzhou Med Univ, Xuzhou Childrens Hosp, Dept Anesthesiol, 18 Sudibei Rd, Xuzhou 221002, Jiangsu, Peoples R China

来源：

MINERVA PEDIATRICA | 2019年 / 71卷 / 05期

关键词：

Pediatrics; HIV infections; Highly active antiretroviral therapy; MEDICATION ADHERENCE; ASSOCIATION; ADOLESCENTS; FORGIVENESS; MANAGEMENT; CLEARANCE; REGIMENS; OUTCOMES; INFANTS; IMPACT;

D O I：

10.23736/S0026-4946.16.04731-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The pediatric highly-active antiretroviral therapy (HAART) has shown enormous progress in recent years but still, a high percentage of children continue to experience treatment failure. The main causes found responsible are the development of drug resistance, inadequate dosing and poor adherence. This review is aimed at exploring the current status of antiretroviral therapy in children with focus on the interaction between disease, drug and patient behavior, all of which are strongly correlated.An overview of HIV viral characteristics and of the available antiretroviral drug classes currently combined to avoid development of resistance has been also discussed.

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页码：455 / 460

页数：6

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