Recent advances in industrial carotenoid synthesis (vol 74. pg 2213, 2002)

被引：68

作者：

Ernst, H ^{[1
]}

机构：

[1] BASF AG, GVFB B, Fine Chem Res, D-67056 Ludwigshafen, Germany

来源：

PURE AND APPLIED CHEMISTRY | 2002年 / 74卷 / 11期

关键词：

D O I：

10.1351/pac200274112213

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Symmetrical C-40-carotenoids are efficiently produced by double Wittig olefination of the corrresponding C-15-phosphonium salts with C-10-dialdehyde. Industrial syntheses of lycopene-, astaxanthin, and (3R,3'R)-zeaxanthin-C-15-phosphonium salts are discussed. An efficient route to a monoprotected C-10-dialdehyde for the synthesis of unsymmetrical C-40-carotenoids is presented. Primary polyene allyl alcohols can be converted to the corresponding aldehydes by "TEMPO" oxidation. A high-yield synthesis of meso-zeaxanthin as an example for syntheses of unsymmetrical carotenoids is presented.

引用

页码：2213 / 2226

页数：14

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