Tritium in [18O]water containing [18F]fluoride for [18F]FDG synthesis

被引：17

作者：

Ito, S

Saze, T

Sakane, H

Ito, S

Nishizawa, K ^{[1
]}

机构：

[1] Nagoya Univ, Radioisotope Res Ctr, Chikusa Ku, Nagoya, Aichi 4648602, Japan

[2] Nagoya Univ, Grad Sch Environm Studies, Chikusa Ku, Nagoya, Aichi 4648602, Japan

[3] Daiyukai Gen Hosp, Dept Radiol, Aichi 4918551, Japan

来源：

APPLIED RADIATION AND ISOTOPES | 2004年 / 61卷 / 06期

关键词：

tritium; F-18]FDG; O-18(p; n); F-18;

D O I：

10.1016/j.apradiso.2004.04.002

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The presence of tritium in enriched [O-18]water irradiated with 9.6 MeV protons used to produce [F-18]fluoride by the O-18(p, n)F-18 reaction was inferred from the cross sections and threshold energies of the O-18(p, t)O-16 reaction, and the existence of tritium was confirmed experimentally. Tritium was also detected in both [O-18]water recovered for recycling and waste acetonitrile solutions. The purified [F-18]FDG was not contaminated with H-3. The amount of H-3 discharged into the air was far less than the International Basic Safety Standard Level. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1179 / 1183

页数：5

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