High-Level Human Herpesvirus-6 Viremia Associated With Onset of Stevens-Johnson Syndrome: Report of Two Cases

被引：15

作者：

Peppercorn, Amanda F. ^{[1
]}

Miller, Melissa B. ^{[2
]}

Fitzgerald, David

Weber, David J. ^{[3
]}

Groben, Pamela A. ^{[2
,4
]}

Cairns, Bruce A. ^{[5
]}

机构：

[1] UNC, Dept Med, Div Infect Dis, Sch Med, Chapel Hill, NC 27599 USA

[2] UNC, Sch Med, Dept Pathol & Lab Med, Chapel Hill, NC 27599 USA

[3] Univ N Carolina Hlth Care, Dept Hosp Epidemiol, Chapel Hill, NC USA

[4] UNC, Sch Med, Dept Dermatol, Chapel Hill, NC 27599 USA

[5] UNC, Sch Med, Dept Surg, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF BURN CARE & RESEARCH | 2010年 / 31卷 / 02期

关键词：

HERPES-SIMPLEX-VIRUS; TOXIC EPIDERMAL NECROLYSIS; ERYTHEMA MULTIFORME; REACTIVATION; HUMAN-HERPESVIRUS-6; INFECTION; ENCEPHALITIS; VARIANT; BLOOD; HBLV;

D O I：

10.1097/BCR.0b013e3181d0f48b

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The pathogenesis of Stevens-Johnson syndrome (SJS) remains obscure, but it has been associated with various infectious agents, including members of the herpesvirus family. We present the first report of high-level human herpesvirus-6 viremia at the onset of SJS, suggesting a possible new association. This finding supports the need for further investigation into the possible relationship between human herpesvirus-6 and SJS, which may illuminate the pathogenesis of SJS and bring us closer to achieving enhanced prevention and treatment of this rare disease. (J Burn Care Res 2010;31:365-368)

引用

页码：365 / 368

页数：4

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