SNH- and SNipso-Arylamination of 1,3,7-Triazapyrenes

被引：21

作者：

Borovlev, Ivan ^{[1
]}

Demidov, Oleg ^{[1
]}

Saigakova, Nadezhda ^{[1
]}

Amangasieva, Gulminat ^{[1
]}

机构：

[1] North Caucasus Fed Univ, Dept Chem, Stavropol 355029, Russia

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 2014卷 / 34期

关键词：

Amination; Aromatic substitution; Nucleophilic substitution; Nitrogen heterocycles; Polycycles; NUCLEOPHILIC AROMATIC-SUBSTITUTION; PALLADIUM-CATALYZED AMINATION; OXIDATIVE ALKYLAMINATION; 7-ALKYL-1,3,7-TRIAZAPYRENIUM SALTS; HYDROGEN; NITROQUINOLINES; HYDROXYLATION; ALKOXYLATION; ANNELATION; ACIDITIES;

D O I：

10.1002/ejoc.201402891

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ability of the oxidative arylamination process to derivatize electron-deficient 1,3,7-triazapyrenes has been investigated. These triazapyrenes react with a wide range of sodium aryl(hetaryl) amides to give access to the corresponding 6-aryl(hetaryl)amino-1,3,7-triazapyrenes in moderate to good yields. The reaction of 6,8-dialkoxy-1,3,7-triazapyrene with sodium arylamides gives rise to 6,8-bis(arylamino)-1,3,7-triazapyrenes or 6-methoxy-8-arylamino-1,3,7-triazapyrenes, depending on the reaction conditions.

引用

页码：7675 / 7683

页数：9

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