Spectroscopic Behavior and Biological Activity of K2[VO(O2)NTA]•2H2O

被引：8

作者：

Arrambide, Gabriel ^{[2
]}

Barrio, Daniel A. ^{[1
]}

Etcheverry, Susana B. ^{[1
,3
]}

Gambino, Dinorah ^{[2
]}

Baran, Enrique J. ^{[3
]}

机构：

[1] Univ Nacl La Plata, Fac Ciencias Exactas, Catedra Bioquim Patol, RA-1900 La Plata, Argentina

[2] Univ Republica, Fac Quim, Dept Estrella Campos, Catedra Quim Inorgan, Montevideo 11800, Uruguay

[3] Univ Nacl La Plata, Fac Ciencias Exactas, Ctr Quim Inorgan, CONICET, RA-1900 La Plata, Argentina

来源：

BIOLOGICAL TRACE ELEMENT RESEARCH | 2010年 / 136卷 / 02期

关键词：

Oxovanadium(V) complex; Vibrational spectra; Electronic spectra; Cells in culture; PHOSPHATASE-ACTIVITY; VANADIUM COMPOUNDS; ANTITUMOR-ACTIVITY; GROWTH-FACTOR; PROLIFERATION; COMPLEXES; TOXICITY;

D O I：

10.1007/s12011-009-8538-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The dihydrated potassium salt of the complex anion [VO(O-2)NTA](2-) (NTA = nitrilotriacetate anion, [N(CH2-COO)(3)](3-)) was thoroughly characterized by electronic and vibrational (infrared and Raman) spectroscopies. The bioactivity of the complex on the cell proliferation was tested on three cell lines in culture (UMR106 rat osteosarcoma-derived cells, Caco-2 derived from a human colon adenocarcinoma, and RAW 264.7, a macrophage murine cell line).

引用

页码：241 / 248

页数：8

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