Towards a total synthesis of the manadomanzamine alkaloids: the first asymmetric construction of the pentacyclic indole core

被引：19

作者：

Allin, Steven M. ^{[1
]}

Duffy, Liam J.

Bulman Page, Philip C.

McKee, Vickie

McKenzie, Michael J.

机构：

[1] Univ Loughborough, Dept Chem, Loughborough LE11 3TU, Leics, England

[2] Charnwood Mol Ltd, Loughborough LE11 5GA, Leics, England

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 27期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/j.tetlet.2007.05.030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report a highly diastereoselective approach for the synthesis of the pentacyclic indole core of the manadomanzamine alkaloid skeleton, with complete control over the relative and absolute stereochemistries at the three contiguous stereocentres at ring positions 1, 10, and 24, from a readily available chiral template. Crown Copyright (c) 2007 Published by Elsevier Ltd. All rights reserved.

引用

页码：4711 / 4714

页数：4

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