Toxoplasma gondii: How fatal is it in pediatric allogeneic bone marrow transplantation setting?

被引:6
作者
Komitopoulou, Anna [1 ]
Goussetis, Evgenios [1 ]
Oikonomopoulou, Christina [1 ]
Paisiou, Anna [1 ]
Kaisari, Katerina [1 ]
Ioannidou, Eleni [1 ]
Sipsas, Nikolaos V. [2 ,3 ]
Kosmidis, Helen [4 ]
Vessalas, Georgios [1 ]
Peristeri, Ioulia [1 ]
Kitra, Vassiliki [1 ]
机构
[1] Agia Sofia Childrens Hosp, Stem Cell Transplant Unit, Mikras Asias 46 & Levadias 8, Athens 11527, Greece
[2] Natl & Kapodistrian Univ Athens, Laikon Gen Hosp, Dept Pathophysiol, Infect Dis Unit, Athens, Greece
[3] Natl & Kapodistrian Univ Athens, Sch Med, Athens, Greece
[4] MITERA Hosp, Pediat Oncol Dept, Athens, Greece
关键词
pediatric; Toxoplasmosis; transplantation; STEM-CELL TRANSPLANTATION; CEREBRAL TOXOPLASMOSIS; MOLECULAR DIAGNOSIS; PROPHYLAXIS; RECIPIENTS; INFECTION; FORGET; CHILD; STILL;
D O I
10.1111/tid.13226
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Toxoplasmosis is a disease of the immunocompetent population. However, cases of toxoplasma infection associated with immunosuppression have been reported, especially the first months after transplantation. Limited data are available about toxoplasma infection, occurring even many months post-transplant in pediatric patients with nonmalignant and malignant diseases. We report the cases of three patients with early and late disseminated toxoplasmosis and review the literature.
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页数:6
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共 40 条
  • [1] [Anonymous], 2019, GUID PREV TREATM OPP
  • [2] Changing the outcome of toxoplasmosis in bone marrow transplant recipients
    Aoun, M.
    Georgala, A.
    Mboumi, K.
    De Bruyne, J. M.
    Duchateau, V.
    Lemort, M.
    Martiat, P.
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2006, 27 (06) : 570 - 572
  • [3] Successful toxoplasmosis prophylaxis after orthotopic cardiac transplantation with trimethoprim-sulfamethoxazole
    Baden, LR
    Katz, JT
    Franck, L
    Tsang, S
    Hall, M
    Rubin, RH
    Jarcho, J
    [J]. TRANSPLANTATION, 2003, 75 (03) : 339 - 343
  • [4] Toxoplasmosis in cord blood transplantation recipients
    Bautista, G.
    Ramos, A.
    Fores, R.
    Regidor, C.
    Ruiz, E.
    de Laiglesia, A.
    Navarro, B.
    Bravo, J.
    Portero, F.
    Sanjuan, I.
    Fernandez, M. N.
    Cabrera, R.
    [J]. TRANSPLANT INFECTIOUS DISEASE, 2012, 14 (05) : 496 - 501
  • [5] Cord blood transplants supported by co-infusion of mobilized hematopoietic stem cells from a third-party donor
    Bautista, G.
    Cabrera, J. R.
    Regidor, C.
    Fores, R.
    Garcia-Marco, J. A.
    Ojeda, E.
    Sanjuan, I.
    Ruiz, E.
    Krsnik, I.
    Navarro, B.
    Gil, S.
    Magro, E.
    de Laiglesia, A.
    Gonzalo-Daganzo, R.
    Martin-Donaire, T.
    Rico, M.
    Millan, I.
    Fernandez, M. N.
    [J]. BONE MARROW TRANSPLANTATION, 2009, 43 (05) : 365 - 373
  • [6] Acute Encephalopathy in the Immune-compromised Child: Never Forget Toxoplasmosis
    Caselli, Desiree
    Andreoli, Elisabetta
    Paolicchi, Olivia
    Savelli, Sara
    Guidi, Stefano
    Pecile, Patrizia
    Arico, Maurizio
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2012, 34 (05) : 383 - 386
  • [7] Centers for Disease Control and Prevention (CDC), PAR TOX
  • [8] Disseminated toxoplasmosis in marrow recipients: A report of three cases and a review of the literature
    Chandrasekar, PH
    Momin, F
    Karanes, C
    Abella, S
    Ratanatharathorn, V
    Sensenbrenner, L
    [J]. BONE MARROW TRANSPLANTATION, 1997, 19 (07) : 685 - 689
  • [9] A matched case-control study of toxoplasmosis after allogeneic haematopoietic stem cell transplantation: still a devastating complication
    Conrad, A.
    Le Marechal, M.
    Dupont, D.
    Ducastelle-Lepretre, S.
    Balsat, M.
    Labussiere-Wallet, H.
    Barraco, F.
    Nicolini, F. -E.
    Thomas, X.
    Gilis, L.
    Chidiac, C.
    Ferry, T.
    Wallet, F.
    Rabodonirina, M.
    Salles, G.
    Michallet, M.
    Ader, F.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2016, 22 (07) : 636 - 641
  • [10] de Medeiros B C, 2001, Transpl Infect Dis, V3, P24, DOI 10.1034/j.1399-3062.2001.003001024.x