Single dose methotrexate therapy: application to interstitial ectopic pregnancy

被引:6
|
作者
Borgatta, L [1 ]
Burnhill, M
Stubblefield, P
机构
[1] Boston Med Ctr, Dept Obstet & Gynecol, Boston, MA USA
[2] Planned Parenthood Federat Amer, Div Med, New York, NY USA
关键词
methotrexate; interstitial pregnancy; ectopic pregnancy;
D O I
10.1016/S0020-7292(97)00274-9
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A woman with a small (6-mm gestational sac) interstitial pregnancy had complete resolution after medical therapy alone. A single cycle of methotrexate 50 mg/m(2) was used as outpatient treatment without any operative procedure either for diagnosis or intervention. The guidelines that have evolved for selection of women for single dose methotrexate treatment for both intrauterine and tubal ectopic pregnancies may be applicable to interstitial ectopic pregnancy as well. A suggested framework for treatment decisions is presented. (C) 1998 International Federation of Gynecology and Obstetrics.
引用
收藏
页码:279 / 282
页数:4
相关论文
共 50 条
  • [41] Methotrexate embryopathy after therapy for misdiagnosed ectopic pregnancy
    Usta, I. M.
    Nassar, A. H.
    Yunis, K. A.
    Abu-Musa, A. A.
    INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2007, 99 (03) : 253 - 255
  • [42] Serum β-hCG levels post-treatment of ectopic pregnancy with a single dose of intramuscular methotrexate
    Hadinata, Ignatius E.
    Doyle, Lex W.
    Thompson, Derrick
    Reti, Leslie
    AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 2015, 55 (02) : 181 - 184
  • [43] High folic acid levels and failure of single-dose methotrexate treatment in ectopic pregnancy
    Takacs, P
    Rodriguez, L
    INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2005, 89 (03) : 301 - 302
  • [44] Morbid obesity and outcome of ectopic pregnancy following capped single-dose regimen methotrexate
    Luis R. Hoyos
    Mokerrum Malik
    Marvin Najjar
    Javier Rodriguez-Kovacs
    Mazen Abdallah
    Gustavo Vilchez
    Awoniyi O. Awonuga
    Archives of Gynecology and Obstetrics, 2017, 295 : 375 - 381
  • [45] Evaluation of the relationship between endometrial thickness and failure of single-dose methotrexate in ectopic pregnancy
    Takacs P.
    Chakhtoura N.
    De Santis T.
    Verma U.
    Archives of Gynecology and Obstetrics, 2005, 272 (4) : 269 - 272
  • [46] The impact of salpingectomy and single-dose systemic methotrexate treatments on ovarian reserve in ectopic pregnancy
    Sahin, Cagdas
    Taylan, Enes
    Akdemir, Ali
    Ozgurel, Banu
    Taskiran, Dilek
    Ergenoglu, Ahmet M.
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2016, 205 : 150 - 152
  • [47] Unilateral tubal twin ectopic pregnancy treated with single-dose methotrexate
    Arikan, Deniz Cemgil
    Kiran, Gurkan
    Coskun, Ayhan
    Kostu, Bulent
    ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2011, 283 (02) : 397 - 399
  • [48] Effect of single-dose methotrexate on ovarian reserve in women with ectopic pregnancy
    Uyar, Ibrahim
    Yucel, Onur Umut
    Gezer, Cenk
    Gulhan, Ibrahim
    Karis, Buket
    Hanhan, H. Merih
    Ozeren, Mehmet
    FERTILITY AND STERILITY, 2013, 100 (05) : 1310 - 1313
  • [49] Comparison of alternative βhCG follow-up protocols after single-dose methotrexate therapy for tubal ectopic pregnancy
    Yavuz Emre Şükür
    Kazibe Koyuncu
    Mehmet Murat Seval
    Esra Çetinkaya
    Fulya Dökmeci
    Archives of Gynecology and Obstetrics, 2017, 296 : 1161 - 1165
  • [50] Single Versus Two-Dose Methotrexate in Ectopic Pregnancy Treatment: Meta-analysis
    Sibel Balcı
    Görker Sel
    Current Obstetrics and Gynecology Reports, 2021, 10 : 107 - 114