Efficacy of cefquinome for-the treatment of bovine mastitis -: a field study

The efficacy of cefquinome for the treatment of bovine mastitis was investigated in afield trial. This involved the treatment of 325 quarters of 215 cows by veterinarians using two regimes, one by intramammary instillation and the other using local and systemic therapy. The efficacy was evaluated using clinical and microbiological examinations and by the California-Mastitis-Test carried out 14 and 21 days after the end of treatment. Intramammary administration was successful in cases of subclinical mastitis, especially staphylococcal mastitis for which there was an 86.3% microbiological cure rate. Combined therapy produced microbiological and clinical cure rates of 69.4 and 94.4% in cases of acute mastitis and of 71.2 and 67.1% in cases of chronic mastitis, respectively. The antimicrobial sensitivity of the 183 staphylococci, 119 streptococci and 23 enterobacterial isolates to cefquinome was examined using the agar diffusion test. All strains were highly sensitive, except one streptococcus.