A 3-D finite element Poisson-Nernst-Planck model for the analysis of ion transport across ionic channels

被引：2
|
作者：
Coco, Salvatore [1 ]
Gazzo, Daniela [1 ]
Laudani, Antonino [1 ]
Pollicino, Giuseppe [1 ]
机构：
[1] Univ Catania, DIEES, I-95125 Catania, Italy
来源：
IEEE TRANSACTIONS ON MAGNETICS | 2007年 / 43卷 / 04期
关键词：
finite element method; ion transport; membrane ionic channel; Poisson-Nernst-Planck model;
D O I：
10.1109/TMAG.2007.891402
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
A 3-D finite element steady-state Poisson-Nernst-Planck model is presented and applied to the analysis of the ion transport across ionic channels of the cellular membrane. The model allows us to obtain an accurate description of ion flow across the cell membrane. An example of application to the case of a K+ channel is also illustrated. The resulting current-voltage relationship for the K+ channel shows excellent agreement with experimental measurements.
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页码：1461 / 1464
页数：4
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