Maintenance therapy for long-term control of high-grade endometrial stromal sarcoma

被引：1

作者：

Nakanishi, Kazuho ^{[1
]}

Maeoka, Yuri ^{[1
]}

Yamada, Takashi ^{[1
]}

Suzuki, Shunji ^{[2
]}

机构：

[1] Nippon Med Sch, Chiba Hokusoh Hosp, Obstet & Gynecol, Inzai, Japan

[2] Nippon Med Coll Hosp, Obstet & Gynecol, Bunkyo Ku, Tokyo, Japan

来源：

BMJ CASE REPORTS | 2022年 / 15卷 / 05期

关键词：

Gynecological cancer; Cancer; see Oncology; Chemotherapy; PHASE-III; CARBOPLATIN; PATIENT; CANCER; TRIAL;

D O I：

10.1136/bcr-2022-248971

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

High-grade endometrial stromal sarcoma (HG-ESS) is a malignant uterine tumour with a poor prognosis. This study aimed to demonstrate the usefulness of maintenance chemotherapy with paclitaxel (PTX) and carboplatin (CBDCA) for HG-ESS recurrence, by examining a case of HG-ESS tumour progression as a result of maintenance therapy interruption because of the COVID-19 pandemic. The patient was a woman in her 60s who presented with lower abdominal pain, nausea and a pelvic tumour, which was diagnosed as HG-ESS. Chemotherapy with PTX (175 mg/m(2) day 1) + CBDCA (area under the concentration-time curve 5 day 1) every 21-28 days (TC therapy) was administered for long-term maintenance of HG-ESS. After 26 cycles, chemotherapy had to be postponed because of the COVID-19 pandemic, thus leading to disease progression and eventually death. In conclusion, TC therapy can prolong survival in patients with HG-ESS, and maintenance chemotherapy should not be postponed.

引用

页数：5

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[21] Long-term multidisciplinary treatment including proton therapy for a recurrent low-grade endometrial stromal sarcoma and pathologically prominent epithelial differentiation: an autopsy case report [J].

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Ogino, Hiroyuki .

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[22] Long-term multidisciplinary treatment including proton therapy for a recurrent low-grade endometrial stromal sarcoma and pathologically prominent epithelial differentiation: an autopsy case report [J].

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[23] COGNITIVE-FUNCTIONING IN LONG-TERM SURVIVORS OF HIGH-GRADE GLIOMA [J].

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[24] High-grade transformation of low-grade endometrial stromal sarcomas lacking YWHAE and BCOR genetic abnormalities [J].

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Stewart, Colin J. R. ;

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Oliva, Esther ;

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[25] High-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy: a case report [J].

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[27] Frequent Homologous Recombination Deficiency in High-grade Endometrial Carcinomas [J].

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Auguste, Aurelie ;

van Wijk, Lise M. ;

Schouten, Philip C. ;

Meijers, Matty ;

ter Haar, Natalja T. ;

Smit, Vincent T. H. B. M. ;

Nout, Remi A. ;

Glaire, Mark A. ;

Church, David N. ;

Vrieling, Harry ;

Job, Bastien ;

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de Kroon, Cor D. ;

Rouleau, Etienne ;

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