Gene delivery to the corneal endothelium

被引：32
作者：
George, AJT
Arancibia-Cárcamo, CV
Awad, HM
Comer, RM
Fehevari, Z
King, WJ
Kadifachi, M
Hudde, T
Kerouedan-Lebossé, C
Mirza, F
Oral, HB
Rayner, SA
Tan, PH
Tay, E
Larkin, DFP
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Div Med, Dept Immunol, London W12 0NN, England
[2] Moorfields Eye Hosp, London, England
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2000年 / 162卷 / 04期
关键词：
D O I：
10.1164/ajrccm.162.supplement_3.15tac11
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Gene transfer to the corneal endothelium has potential for modulating rejection of corneal grafts. It can also serve as a convenient and useful model for gene therapy of other organs. In this article we review the work carried out in our laboratory using both viral and nonviral vectors to obtain gene expression in the cornea.
引用
收藏
页码：S194 / S200
页数：7
相关论文
共 53 条
  • [1] ABRAHAM NG, 1995, INVEST OPHTH VIS SCI, V36, P2202
  • [2] Lipoadenofection-mediated gene delivery to the corneal endothelium:: Prospects for modulating graft rejection
    Arancibia-Cárcamo, CV
    Oral, HB
    Haskard, DO
    Larkin, DFP
    George, AJT
    [J]. TRANSPLANTATION, 1998, 65 (01) : 62 - 67
  • [3] Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5
    Bergelson, JM
    Cunningham, JA
    Droguett, G
    KurtJones, EA
    Krithivas, A
    Hong, JS
    Horwitz, MS
    Crowell, RL
    Finberg, RW
    [J]. SCIENCE, 1997, 275 (5304) : 1320 - 1323
  • [4] Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers
    Bielinska, A
    KukowskaLatallo, JF
    Johnson, J
    Tomalia, DA
    Baker, JR
    [J]. NUCLEIC ACIDS RESEARCH, 1996, 24 (11) : 2176 - 2182
  • [5] The interaction of plasmid DNA with polyamidoamine dendrimers: mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA
    Bielinska, AU
    KukowskaLatallo, JF
    Baker, JR
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1997, 1353 (02): : 180 - 190
  • [6] Borras T, 1996, INVEST OPHTH VIS SCI, V37, P1282
  • [7] Receptor ligand-facilitated gene transfer: Enhancement of liposome-mediated gene transfer and expression by transferrin
    Cheng, PW
    [J]. HUMAN GENE THERAPY, 1996, 7 (03) : 275 - 282
  • [8] Fehervari Z, 1997, CORNEA, V16, P459
  • [9] FORRESTER J, 1996, EYE BASIC SCI PARCTI
  • [10] Peptide-mediated non-viral gene transfer for transplantation
    George, AJT
    [J]. TRANSPLANTATION, 2000, 69 (06) : 1031 - 1033
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