Crystallization of citrate-stabilized amorphous calcium phosphate to nanocrystalline apatite: a surface-mediated transformation

被引：62

作者：

Chatzipanagis, Konstantinos ^{[1
]}

Iafisco, Michele ^{[2
]}

Roncal-Herrero, Teresa ^{[1
]}

Bilton, Matthew ^{[1
,3
]}

Tampieri, Anna ^{[2
]}

Kroger, Roland ^{[1
]}

Manuel Delgado-Lopez, Jose ^{[4
]}

机构：

[1] Univ York, Dept Phys, York YO10 5DD, N Yorkshire, England

[2] Natl Res Council CNR, Inst Sci & Technol Ceram ISTEC, Faenza, Italy

[3] Simon Fraser Univ, Dept Chem, Burnaby, BC V5A 1S6, Canada

[4] CSIC UGR, IACT, Lab Estudios Cristalog, Granada, Spain

来源：

CRYSTENGCOMM | 2016年 / 18卷 / 18期

基金：

英国工程与自然科学研究理事会; 欧盟第七框架计划;

关键词：

RAMAN MICROSPECTROSCOPY; BONE APATITE; HYDROXYAPATITE; MINERALIZATION; PRECIPITATION; BIOMATERIALS; NUCLEATION; CONVERSION; KINETICS; SITES;

D O I：

10.1039/c6ce00521g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This work explores the mechanisms underlying the crystallization of citrate-functionalized amorphous calcium phosphate (cit-ACP) in two relevant media, combining in situ and ex situ characterization techniques. Results demonstrate that citrate desorption from cit-ACP triggers the surface-mediated transformation to nanocrystalline apatite (Ap). Our findings shed light on the key role of citrate, an important component of bone organic matrix, and the medium composition in controlling the rate of transformation and the morphology of the resulting Ap phase.

引用

页码：3170 / 3173

页数：4

共 33 条

[1] Granulation, Phase Change, and Microstructure - Kinetics of Phase Change. III
Avrami, M
[J]. JOURNAL OF CHEMICAL PHYSICS, 1941, 9 (02) : 177 - 184
[2] Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situ Raman microspectroscopy
Belen Ramirez-Rodriguez, Gloria
Manuel Delgado-Lopez, Jose
Gomez-Morales, Jaime
[J]. CRYSTENGCOMM, 2013, 15 (12): : 2206 - 2212
[3] Transient amorphous calcium phosphate in forming enamel
Beniash, Elia
Metzler, Rebecca A.
Lam, Raymond S. K.
Gilbert, P. U. P. A.
[J]. JOURNAL OF STRUCTURAL BIOLOGY, 2009, 166 (02) : 133 - 143
[4] CONVERSION OF AMORPHOUS CALCIUM PHOSPHATE TO MICROCRYSTALLINE HYDROXYAPATITE - PH-DEPENDENT, SOLUTION-MEDIATED, SOLID-SOLID CONVERSION
BOSKEY, AL
POSNER, AS
[J]. JOURNAL OF PHYSICAL CHEMISTRY, 1973, 77 (19) : 2313 - 2317
[5] Stabilizing amorphous calcium phosphate phase by citrate adsorption
Chen, Yan
Gu, Wenjia
Pan, Haihua
Jiang, Shuqin
Tang, Ruikang
[J]. CRYSTENGCOMM, 2014, 16 (10): : 1864 - 1867
[6] Amorphous calcium phosphates: Synthesis, properties and uses in biomaterials
Combes, C.
Rey, C.
[J]. ACTA BIOMATERIALIA, 2010, 6 (09) : 3362 - 3378
[7] Citrate bridges between mineral platelets in bone
Davies, Erika
Mueller, Karin H.
Wong, Wai Ching
Pickard, Chris J.
Reid, David G.
Skepper, Jeremy N.
Duer, Melinda J.
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (14) : E1354 - E1363
[8] Amorphous calcium (ortho)phosphates
Dorozhkin, Sergey V.
[J]. ACTA BIOMATERIALIA, 2010, 6 (12) : 4457 - 4475
[9] BONE MINERALIZATION Water brings order
Duer, Melinda
Veis, Arthur
[J]. NATURE MATERIALS, 2013, 12 (12) : 1081 - 1082
[10] Progress on the preparation of nanocrystalline apatites and surface characterization: Overview of fundamental and applied aspects
Gomez-Morales, Jaime
Iafisco, Michele
Manuel Delgado-Lopez, Jose
Sarda, Stephanie
Drouet, Christophe
[J]. PROGRESS IN CRYSTAL GROWTH AND CHARACTERIZATION OF MATERIALS, 2013, 59 (01) : 1 - 46

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