Bilateral Testicular Metastases and Filariasis in Prostatic Adenocarcinoma

Testicular metastasis from a solid malignancy is a rare entity. The most common presentation of testicular metastasis is a unifocal and unilateral lesion. We report a case of bilateral testicular metastases with associated filariasis in a patient with prostatic adenocarcinoma and skeletal metastases. To the best of our knowledge, this is the only case of bilateral testicular metastases from prostate cancer with coexisting filariasis reported in the published The presence of filarial worms might have resulted in an inflammatory reaction that caused lymphangiectasia or lymphatic obstruction, creating a microenvironment conducive to the retrograde lymphatic spread of the tumor emboli. (C) 2016 Elsevier Inc. All rights reserved.