Uterine synechiae after intrauterine device use: a case series

被引:1
作者
Abel, Mary Kathryn [1 ,2 ]
Wald, Kaitlyn [1 ]
Cedars, Marcelle I. [1 ]
Noel, Martha [1 ]
机构
[1] Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, 499 Illinois St,6th Floor, San Francisco, CA 94158 USA
[2] Univ Calif San Francisco, Sch Med, 533 Parnassus Ave, San Francisco, CA 94143 USA
关键词
Intrauterine device; Infertility; Intrauterine adhesions; Asherman syndrome;
D O I
10.1007/s10815-021-02173-6
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Purpose The intrauterine device (IUD) is one of the most effective and safe contraceptive methods. Substantial literature suggests an overall return to normal fertility following IUD removal. However, there are no studies to date that evaluate endometrial function specifically in nulliparous women after levonorgestrel IUD use. Methods We present three nulliparous women with a history of levonorgestrel IUD use who were evaluated for uterine dysfunction at the University of California, San Francisco Center for Reproductive Health. These patients had no other known risk factors or history of uterine manipulation, including prior uterine surgery, pelvic radiation, intrauterine infection, hypothalamic amenorrhea, or uterine anomaly. Results Upon evaluation, these patients were found to have uterine synechiae concerning for Asherman syndrome. All three patients were eventually able to conceive through assisted reproductive technology or natural conception. Conclusion This case series is the first to suggest a possible effect of endometrial dysfunction on fertility resumption following levonorgestrel IUD removal in nulliparous patients. It is possible that a small subset of patients may be at risk for Asherman syndrome after IUD use. Larger prospective trials are needed to explore this possible association.
引用
收藏
页码:2625 / 2629
页数:5
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